Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2009-06-09
2011-12-06
Bowman, Amy (Department: 1635)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S023100, C435S320100, C435S325000, C514S04400A
Reexamination Certificate
active
08071753
ABSTRACT:
The present invention relates to nucleic acid sequences producing at least one functional miRNA, at least one functional shRNA and/or at least one functional siRNA, said miRNA, shRNA or siRNA being designed to silence the expression of a gene that encodes a cholinergic protein. The present invention further relates to compositions and kits comprising such nucleic acid sequences as well as to uses thereof.
REFERENCES:
Inazu et al. (Journal of Neurochemistry, 2005, 94, pp. 1427-1437).
Scherr et al. (Cell Cycle, 2:3, 251-257, 2003).
Ziabreva et al. (Journal of Psychosomatic Research, 61, 2006, 311-316.
Akkina et al. (J Virol., 1996, 70(4), 2581-5).
Bierer et al., J. Neurochem. 64:749-760 (1995).
Schlieb et al., J. Neural Transm. 113:1625-1644 (2006).
Brandon et al., J. Neurosci. 23:539-549 (2003).
Brice et al., J. Neurosci. Res. 23:266-273 (1989).
Brummelkamp et al., Science 296:550-553 (2002).
Clark et al., . Journal of Neurochemistry 102:112-120 (2007).
Dykxhoorn et al., Nat. Rev. Mol. Cell Biol. 4:457-467 (2003).
Heckers et al., J Neurosci. 14:1271-1289 (1994).
McCann et al., Proceedings of the National Academy of Sciences of the United States of America 103:5149-5154 (2006).
Misgeld et al., Neuron 36:635-648 (2002).
Parent et al., Learning & Memory 11:9-20 (2004).
Waite et al., Life Sciences 58:1947-1953 (1996).
Walsh et al., Brain Research 702:233-245 (1995).
Wiley et al., Brain Research 562:149-153 (1991).
Wrenn et al., Brain Research 847:284-298 (1999).
Mallet et al., Acta Physiologica 191(Supp. 658):SW05-23 (2007), Abstract only.
Berrard Sylvie
Lecomte Marie José
Mallet Jacques
Santamaria Julie
Bowman Amy
Centre National de la Recherche Scientifique
Pelto Don J.
Sheppard Mullin Richter & Hampton LLP
LandOfFree
RNAi mediated expression inhibition of a cholinergic protein does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with RNAi mediated expression inhibition of a cholinergic protein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and RNAi mediated expression inhibition of a cholinergic protein will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4307934