RNA polymerase transcription factor

Details RNA polymerase transcription factor RNA polymerase transcription factor

1995-09-07

1998-08-11

Elliott, George C.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

530350, C12N 900, C07K 1447

Patent

active

057926344

ABSTRACT:
A new RNA polymerase transcription factor has been discovered. The enzyme significantly increases the rate of transcription elongation by RNA polymerase II.

REFERENCES:
Ngo et al., The protein Folding Problem and Tertiaky Structure Prediction, 1994, Mertz et al. (ed.) Birkhauser, Boston, MA, pp. 433 and 492-495.
Bengal et al., "Role of mammalian transcription factors IIF, IIS, and IIX during elongation by RNA polymerase II," Mol Cell Biol 11:1195-1206(1991).
Bradsher et al., "RNA polymerase II transcription factor SIII," J Biol Chem 268:25587-25593 (1993).
Buratowski, S. "DNA repair and transcription: the helicase connection," Science 260:37-38 (1993).
Chafin et al, "Identification and purification of a yeast protein that affects elongation by RNA polmerase, II," J Biol Chem 266:9256-9262 (1991).
Conaway et al., "Transcription factor SIII: a novel component of the RNA polymerase, II elongation complex," Cell Mol Biol Res 39:323-329 (1993).
Garrett, et al., "Molecular cloning of an essential subunit of RNA polymerase II elongation factor SIII," Proc Natl Acad Sci USA 91:5237-5241 (1994).
Gerard et al., "Purification and interaction properties of the human RNA polymerase B(II) general transcription factor BRF2," J Biol Chem 266:20940-20945 (1991).
Krauskopf et al., "The block to transcription elongation at the minute virus of mice attenuator is regulated by cellular elongation factors," Mol Cell Biol 11:3515-3521 (1991).
Madore et al., "Genetic analysis of the cofactor requirement for human immunodeficiency virus type I Tat function," J Virology 67:3703-3711 (1993).
Natori et al., "DNA dependent RNA polymerase from Ehrlich ascites tumor cells," J Biochem 73:879-888 (1973).
Rosen, C.A., "HIV regulator proteins: potential targets for therapeutic intervention," AIDS Research and Human Retroviruses 8:175-181 (1992).
Schaeffer et al., "DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor," Science 260:58-63 (1993).
Sekimizu et al., "Purification of a factor from Ehrlich ascites tumor cells specifically stimulating RNA polmerase, II," Biochemistry 15:5064-5070 (1976).
Wright, S., "Regulation of eukaryotic gene expression by transcriptional attenuation," Molecular Biology of the Cell 4:661-668 (1993).

Affiliated with

Also associated with

Rating

RNA polymerase transcription factor does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with RNA polymerase transcription factor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and RNA polymerase transcription factor will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-388082