RNA-dependent amidotransferase from Staphylococcus aureus

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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435 691, 435440, 435455, 435471, 435325, 4352523, 43525411, 4353201, 536 231, 536 232, 536 237, A61K 4800, C12N 1554, C12N 1531, C12N 1563

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active

061503401

ABSTRACT:
The invention provides ratA polypeptides and DNA (RNA) encoding ratA polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ratA polypeptides to screen for antibacterial compounds.

REFERENCES:
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Rudinger, "Characteristics of the amino acid as componants of a peptide hormone sequence", in Peptide Hormones, Parsons (ed.), University Park Press: Baltimore, MD, pp. 1-7, Jun. 1976.
Ben-Yedidia et al., "Design of peptide and polypeptide vaccines", Curr. Opin. Biotechnol. 8: 442-448, 1997.
Wengender et al., "Identification of a PutP proline permease gene homolog from Staphylococcus aureus by expression cloning of the high-affinity proline transport system in Escherichia coli", Appl., Environ. Microbiol. 61 (1): 252-259, Jan. 1995.
Tabata, S., GenBank Submission, Accession Number D90907 AB001339 "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803.II. Sequence determination of the entire genome and assignment of potential protein-coding regions".
Hajime, et al., "Isolation and Identification of Antimicrobial Compounds in Brazilian Propolis", Biosci. Biotech. Biochem., vol. 58, No. 5, pp. 945-946, (1994).
Sevier, et al., "Monoclonal Antibodies in Clinical Immunology", Clinical Chemistry, vol. 27, No. 11, pp. 1797-1806, (1981).

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