Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...
Patent
1995-06-07
2000-10-17
Navarro, Albert
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Fungus, except allergen, or component thereof or substance...
4241841, 424 935, 424 933, 424 931, A61K 3900, A61K 3938, A01N 6300, A01N 6500
Patent
active
061327336
ABSTRACT:
A ringworm vaccine is disclosed comprising antigen isolated from at least one dermatophyte and a suitable carrier. The "antigen" can include a single antigen from a dermatophyte or a plurality of antigens as long as at least one antigen is included which will produce a sufficient immune response to confer resistance to ringworm infection upon the recipient of the vaccine. The antigen can also be isolated from more than one dermatophyte. If a preparation from more than one dermatophyte is made the antigen can include antigens which are common to all species of dermatophytes employed and/or antigens which are only specific to certain species. A method of producing such a ringworm vaccine is also disclosed. The method comprises making an antigen preparation comprising the dermatophyte antigen described above and combining the antigen preparation with a suitable carrier. Methods of treating a patient are also disclosed employing the vaccine of the present invention and vaccines produced according to the method of the present invention. Methods are also disclosed for treating a pregnant patient with such vaccines such that the progeny of the pregnancy exhibit resistance to ringworm infection at birth.
REFERENCES:
patent: 2011225 (1935-08-01), Krueger et al.
patent: 3897550 (1975-07-01), Reynolds
patent: 4368191 (1983-01-01), Sarkisov et al.
Zinsser's text book of microbiology, published 1972 by Appleton-century-copy, New York, N.Y., pp. 206.
Hussin, Z. et al. (1983) Vaccination Procedures and the Infectivity of Dermatophyte Lesions. Mycopathologia 81: 71-76.
Heifits, Y. (1985) Vaccines Against Ringworm. World Health Forum 6:373-374.
Rasulev (1974) Veterinariya Moscow, No. 10:54-56, Immunity to Trichophyton Infection in Cattle (2 versions of Abstract only).
Veterinary Bulletin (Abstract) 43:613 (1973).
Hajsig et al. (1974) Veterinary Bulletin (Abstract) 44:360.
Veterinary Bulletin (1977) (Abstract) 47:123.
Jilavyan et al. (1976) Abstract, Effect of Vaccination Against Ringworm On The Course of Pregnancy In Cows, Byulleten Vsesoyuznogo Institute Eksperimental' noi Veterinarii 25: 28-29.
Mosher, et al. (1977) Treatment Of Ringworm (Microsporum canis) With Inactivated Fungal Vaccine, Vet. Med. 72: 1343-1345.
O'Brien, et al. (1958) A Clinical Trial Of The Treatment Of Cattle Ringworm, Vet. Record. 70:319-321.
Cox, R. A. (1989) Immunology Of The Fungal Diseases. pp. 18, 20-21.
Wharton, et al. (1950) Active Immunization Trichophyton Purpureim Infection In Rabbits. J. Invest. Dermatol. 14:291-303.
Keeney, et al. (1959) Immunization Against Superficial Funguous Infection. J. Invest. Dermatol. 32:7-13.
Cruickshank, et al. (1960) Studies on Trichophytin Sensitivity. J. Invest. Dermatol. 35:219-223.
Podobedov Abstract (1971) Specific Prophylaxis of Cattle Ringworm (using live tricophyton faviforme antigen). Veterinariya 1971, No. 6:48-49.
Kocik (1982) Abstract, Experimental Evaluation Of Live and Killed Vaccines Against Ringworm In Guinea Pigs and Young Cattle, Polskie Archiwum Wet. 72(8) 1343-45.
Brydl, Abstract, The possibility of controlling ringworm infection of cattle by vaccination Magyar Allatorvosok LAPJA 1976 32(7) pp. 441-442.
Rybnikar, et al. (1985) Vet. Med. (Praha) Abstract only, 30:119-28.
Petzcar, Microbiology (1958) p. 276.
Buxton et al. (1977) Dermatomycoses, Animal Microbiology, vol. 1, Chapter 34, Blackwell Scientific Publications, pp. 313-319.
Warren, et al. (1986) Current Status of Immunological Adjuvants, Ann. Rev. Immunol. 4:369-388.
Wilson et al. (1970) The Fungus Diseases of Man, U. of Calif. Press, pp. 216-217.
Taber's Cyclopedic Medical Dictionary, p. 1500, Philadelphia 1989.
Woloszyn et al. (1983) Prevalence and specific prevention of Trichophyton Infextion in Farmed Foxes, Medycyna Weterynaryjna 39:387-91 Abstract only.
Wawrzkiewicz, et al. (1988) Polskie Archiwum Weterynaryjne 28:5-16 Abstract only.
Weiss et al. (1978) The most important dermatophytes and dermatomycoses of domestic animals, Tierdrztliche Praxis, 6:421-433 Abstract only.
Wawrzkiewicz et al. (1987) An In-Vivo Evaluation Of The Virulence Of Trichophyton Strains Abstract only, Medycyna Weterynaryjna 43:667-672.
Pabst et al. (1987) Transfer Of Material Specific Cell-Mediated Immunity To The Fetus Clin. Exp. Immunol. 68:209-214 Abstract only.
Schlamowitz (1976) Membrane Receptors In The Specific Transfer Of Immunoglobulins From Mother To Young, Immunol. Commun. 5:481-500.
Elad et al (1989) Fungal Ribosomal Vaccine, Mycopaltrologia 105:49-51.
Sherding, Editor of The Cat Diseases And Clinical Management, Second Edition, vol. 2 pp. 1931-1937.
Moriello (1994) Update On The Treatment Of Feline Dermatophytosis, 10th Proceedings, Annual Members' Meeting AAVD and ACVD, Charleston, SC.
DeBoer "New Thoughts On Management Of Dermatophytosis In Catteries" presented at Robt. H. Winn Foundation 15th Annual Symposium on Feline Health, Jun. 24, 1993, San Antonio, TX.
Scott (1980) "Feline Dermatology 1900-1978: A Monograph" Jrnl. Amer. Anim. Hosp. Assoc. 16:331, 354-7, 364, 453.
Holt et al. (1990) "Immunization Of Pigs With Killed Cultures of Streptococcus suis type 2" Research in Vet. Science 48:23-27.
Cat Tracks, Autumn 1988 pp. 42-45.
Chanis, J.J. Ph.D. thesis, published Feb. 27, 1989, Library of the J.R. Kovalenko-Research-Institute, Moscow only considered to the extent of abstract May 13, 1999.
Wawrzkiewicz, K. et al., J. Polskie Archivum Weterynarynje, vol. 28, No. 3-4, 1988, pp. 5-16.
Wawrzkiewicz, K. et al., Annales UMCS (Lublin, sectio DD, 39, 53, 1984, pp. 53-63.
Kielstein, P. et al. reprint from the archives for Experimental Veterinary Medicine, vol. 24, No. 5/1970, pp. 1205-1218.
Florian, E. et al., Magyar Allatorvosok Lapja, 19. evf. 12. sz. Dec. 1964, pp. 529-530.
Ibragimov, E. et al., Animal Diseases in Agriculture, vol. XXX, part 1, 1980, Taskent; Editor: Ministry o Agriculture of the Usbec Socialistic Soviet Republic.
Kocik, T., Polskie Archivum Weterynarynje 23, 3, 1982, pp. 95-107.
Uhlein, Rompps Chemisches Worterbuch, 1969, Franckh'sche Verlagshandlung, W. Keller & Co., Stuttgart, p. 366.
Hagers Handbuch der Pharmazeutischen Praxis, 1971, vol. VII, Springer Verlag.
Mayr, A. 35 al., Handbook of Vaccinations in Veterinary Medicine, 1984, Verlag Paul Parey.
Anon, 1988, Willamette Laboratories, 9108 N.E. Sandy Blvd., Portland, OR (USA), Photocopy of typewritten material. Available at: US (Department of Agriculture, National Agricultural Library.
Fort Dodge, Iowa 5051, "Microsporum Canis Vaccine, Killed Fungus, Felo-O-Vax MC-K" product description and "United States Biological Product License".
Strobel Michael
Werner Mark
Jefferson Labs, Inc.
Navarro Albert
LandOfFree
Ringworm vaccine does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Ringworm vaccine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ringworm vaccine will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-465837