Ring-opening amidation process

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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548431, 564189, C07D31744

Patent

active

057771383

ABSTRACT:
corresponding ring-opened amide, is modified by the addition of an additive that accelerates the rate of reaction to an extent that the reaction can be carried out at atmospheric pressure.

REFERENCES:
J. Chen et al., A Novel and Efficient Route to Chiral 2-Substituted Carbocyclic 5'-N-Ethyl-Carboxamido-Adenosine (C-NECA), Tetrahedron Letters, vol. 30, No. 41, 1989, pp. 5543-5546.

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