Ring-expanded nucleosides and nucleotides

Details Ring-expanded nucleosides and nucleotides Ring-expanded nucleosides and nucleotides

1995-08-23

1998-12-01

Kunz, Gary L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 81, 514393, 514421, 536 2713, A61K 3170, A07H 1904, A01N 4336, A01N 43713

Patent

active

058439129

ABSTRACT:
The present invention relates to compositions comprising analogues of purine nucleosides containing a ring-expanded ("fat") heterocyclic ring, in place of purine, and an unmodified or modified sugar residue, pharmaceutically acceptable derivatives of such compositions, as well as methods of use thereof. In particular, these compositions may be utilized in the treatment of certain cancers, bacterial, fungal, parasitic, and viral infections, including, but not limited to, Acquired Immunodeficiency Syndrome (AIDS) and hepatitis.

REFERENCES:
Wang et al. Nucleosides & Nucleotides 13(10): 2307-2320 (1994).

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