Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing a carotene nucleus
Patent
1985-08-22
1988-12-20
Wiseman, Thomas G.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing a carotene nucleus
4351721, 435886, 424115, 424122, 424124, 549294, C12P 2300, C12N 120, A61K 3500
Patent
active
047925221
ABSTRACT:
A novel complex designated herein as rigolettone complex is produced by fermentation of Streptomyces aburaviensis strain C-38,242 (ATCC 39290). The complex and its purified bioactive components, jildamycin and mantuamycin, exhibit antitumor activity in mouse tumor systems.
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patent: 4283390 (1981-08-01), Koch et al.
patent: 4548814 (1985-10-01), Rinehurts Jr.
Hamamoto et al. J Antibiotics, vol. XXXVI, No. 6, Jun. 1983, pp. 639-645, "Leptomycihs A and B, New Antifungal Antibiotics I Taxonomy of the Prducing Strain . . . and Characterization".
Hamamoto et al., J Antibiotics, vol. XXXVI, No. 6, Jun. 1983, pp. 640-650, "Leptomycihs A and B, New Antifungal Antibiotics II Structure Elucidatium".
Bradner William T.
Bray Stanley W.
Bush James A.
Nettleton, Jr. Donald E.
Bristol-Myers Company
Teskin Robin L.
Wiseman Thomas G.
Yang Mollie M.
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