Rifamycin compounds

Details Rifamycin compounds Rifamycin compounds

1976-04-27

1977-04-12

Jiles, Henry R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424244, C07D49808

Patent

active

040174816

ABSTRACT:
Rifamycin compounds having high antibiotic activity, comprising rose-colored powders, water insoluble, but soluble in most of the organic solvents.
Such compounds are obtained by reacting 3-amino-rifamycin S with gaseous ammonia in ethers and/or aromatic hydrocarbons at a temperature between 0.degree. C and +30.degree. C, stirring the mixture for at least 3 hours, and then isolating the compound thus obtained.

REFERENCES:
Kump et al. "Helvetica Chimica Acta" vol. 56, (1973), pp. 2348-2377.

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