Ribozymes targeting bradeion transcripts and use thereof

Details Ribozymes targeting bradeion transcripts and use thereof Ribozymes targeting bradeion transcripts and use thereof

2006-06-27

2006-06-27

McGarry, Sean (Department: 1635)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S023100, C536S024310, C536S024330

Reexamination Certificate

active

07067650

ABSTRACT:
This invention relates to: a set of ribozymes which comprises at least one ribozyme capable of binding and cleaving Bradeion α mRNA which corresponds to DNA comprising a nucleotide sequence shown in SEQ ID NO:1, and at least one ribozyme capable of binding to and cleaving Bradeion β mRNA which corresponds to DNA comprising a nucleotide sequence shown in SEQ ID NO:3; a set of vectors comprising ribozymes; a pharmaceutical composition comprising set of vectors; and a method for treating a subject with a cancer using set of vectors.

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22ndAnnual Meeting of Japan Molecular Biology Society Programs and Abstracts; Dec. 7-10, 1999; Issued Nov. 22, 1999; Sponsored by the organizing Committee for Annual Meeting of Japan Molecular Biology Society.

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