Ribosomes as vectors for RNA

Details Ribosomes as vectors for RNA Ribosomes as vectors for RNA

1996-04-23

1998-04-14

Robinson, Douglas W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

4351723, 435243, 4353201, 435325, 536 242, C07H 2104, C12N 100, C12N 1574, C12N 1579

Patent

active

057393109

ABSTRACT:
Methods and compositions are described for the use of ribosomal RNA as a vehicle for heterologous sequences.

REFERENCES:
patent: 5585479 (1996-12-01), Hoke et al.
Stull et al., "Antigene, Ribozyme and Aptamer Nucleic Acid Drugs: Progress and prospects," Pharma. Res., 12:465-483 (1995).
Sullenger et al., "Expression of Chimeric tRNA-Driven Antisense Transcripts Renders NIH 3T3 Cells Highly Resistant to Moloney Murine Leukemia Virus Replication," Mol. Cell. Biol., 10:6512-6523 (Dec. 1990).
Sweeney R, et al. "Antisense ribosomes: rRNA as a vehicle for antisense RNAs." PNAS 93: 8518-8525, Aug. 1996.
Wakeman JA, et al. "28 S ribosomal RNA in vertebrates." Biochem. J. 258: 49-56, 1989.

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