Ribonucleases and methods of making them recombinantly

Details Ribonucleases and methods of making them recombinantly Ribonucleases and methods of making them recombinantly

2007-06-12

2007-06-12

Ramirez, Delia M. (Department: 1652)

Chemistry: molecular biology and microbiology

Vector, per se

C435S252300, C435S325000, C435S196000, C435S069100, C536S023200, C536S023100, C530S350000

Reexamination Certificate

active

10621741

ABSTRACT:
Methods for recombinantly producing new RNases, as well as previously-known RNases, are disclosed. The new RNases are active against human carcinoma cells.

REFERENCES:
patent: 6239257 (2001-05-01), Ardelt
Lehninger, A.L. (1975) Biochemistry, Second Edition, p. 962.
Studier, F.W., et al. (1990) Met. Enzym. 185, 60-89.
Huang, H-C, et al. (1998) J. Biol. Chem. 273(11), 6395-6401.
Guerro, S.A., et al. (2000) Appl. Microbiol. Biotechnol. 53, 410-414.

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