Ribonuclease resistant RNA preparation and utilization

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

4351723, 4352351, 536 231, 536 241, C12Q 168, C12N 1563, C12N 700, C07H 2104

Patent

active

059392622

ABSTRACT:
The present invention relates to nuclease resistant nucleic acids in general and ribonuclease resistant RNAs in particular. Methods of making and using such nucleic acids are disclosed.

REFERENCES:
patent: 5091309 (1992-02-01), Schlesinger et al.
patent: 5443969 (1995-08-01), Wilson et al.
patent: 5500360 (1996-03-01), Ahlquist et al.
patent: 5578473 (1996-11-01), Palese et al.
patent: 5589367 (1996-12-01), Donson et al.
patent: 5602242 (1997-02-01), Ahlquist et al.
patent: 5614413 (1997-03-01), Morrow
patent: 5618699 (1997-04-01), Hammamoto et al.
patent: 5622705 (1997-04-01), Morrow
patent: 5627060 (1997-05-01), Ahlquist et al.
patent: 5716821 (1998-02-01), Wertz et al.
patent: 5739026 (1998-04-01), Garoff et al.
Peabody, "The RNA binding site of bacteriophage MS2 coat protein," The EMBO Journal 12(2):595-600, 1993.
Marx et al. A study of PhiX-174 DNA torus and lambda DNA torus tertiary structure and the implications for DNA self-assembly. J. Biol. Struct. Dyn. vol. 4(1):23-39, Apr. 1986.
Bender et al. Design of retrovirus vectors for gene transfer. J. Cell. Biochem. Supp. 12B, 161, Feb. 29, 1988.
Shure et al. The problems of eukaryotic and prokaryotic DNA packaging ind in-vivo conformation posed by superhelix density heterogeneity. Nuc. Acids Res. vol. 4(5):1183-1205, Apr. 1977.
Allen et al. A specific RNA structural motif mediates high affinity binding by the HIV-1 nucleocapsid protein (NCp7). Virol. vol. 225:306-315, Nov. 15, 1996.
Winter et al. Bacteriophage T4 regA protein binds to amRNAs and provents translation initiation. PNAS(USA) vol. 84:7822-7826, Nov. 1987.
Weigand et al. Specificty of the S1 nuclease from Aspergillus oryzae. J. Biol. Chem. vol. 250(25):8848-8855, Nov. 25, 1975.
Toscani et al. Normalization of multiple RNA samples using and in-vitro-synthesized external standard cRNA. Anal. Biochem. vol. 165:309-319, Aug. 1987.
Stockley et al. Molecular mechanism of RNA phage morphogenesis. Int J. Biochem. vol. 26(10/11):1249-1260, Dec. 1994.
Mesmaeker et al. Antisense oligonucleotides. Acc. Chem. Res. vol. 28:366-374, Mar. 1995.
Gewirtz et al. Facilitating oligonucleotide delivery: Helping antisense deliver on its promise. PNAS (USA) vol. 93:3161-3163, Apr. 1996.
Pickett et al. Encapsidation of heterologous RNAs by bacteriophage MS2 coat protein. Nuc. Acids Res. vol. 21(19):4621-4626, Oct. 1993.
Argetsinger and Gussin, "Intact Ribonucleic Acid from Defective Particles of Bacteriophage R17," J Mol Biol, 21:421-434, 1966.
Aslanzadeh et al., "Evaluation of PCR and Nested PCR for Laboratory Diagnosis of Hepatitis C Virus Infection," Mol Cell Probes, 10:173-178, 1996.
Barlow et al., "Analysis and Genotyping of PCR Products of the Amplicor HIV-1 Kit," J Virological Methods, 52:65-74, 1995.
Collins et al., "Preparation and Characterization of RNA Standards for Use in Quantitative Branched DNA Hybridization Assays," Analytical Biochemistry, 226:120-129, 1995.
Golmohammadi et al., "The Refined Structure of Bacteriophage MS2 at 2.cndot.8 .ANG. Resolution," J Mol Biol, 234:620-639, 1993.
Heisenberg, "Formation of Defective Bacteriophage Particles by fr Amber Mutants," J. Mol. Biol., 17:136-144, 1966.
Hughes and Andrew, "Creation of Deletion, Insertion and Substitution Mutations Using a Single Pair of Primers and PCR," Biotechniques, 20(2):188-196, 1996.
LeCuyer et al., "Mutants of the Bacteriophage MS2 Coat Protein that Alter its Cooperative Binding," Biochem, 34:10600-10606, 1995.
Lim and Peabody, "Mutations that Increase the Affinity of a Translational Repressor for RNA," Nuc Acids Res, 22(18):3748-3752, 1994.
Lim et al., "Altering the RNA Binding Specificity of a Translational Repressor," J Biol Chem, 269(12):9006-9010, Mar. 1994.
Lu and Andrieu, "Use of the Human Immunodeficiency Virus Virion as a Universal Standard for Viral RNA Quantitation by Reverse Transcription-Linked Polymerase Chain Reaction," J Infect Diseases, 167:1499-1500, 1993.
Mastico et al., "Multiple Presentation of Foreign Peptides on the Surface of an RNA-Free Sphereical Bacteriophage Capsid," J General Virology, 74:541-548, 1993.
Mellors et al., "Prognosis in HIV-1 Infection Predicted by the Quantity of Virus in Plasma," Science, 272:1167-1170, May 1996.
Mulder et al., "Rapid and Simple PCR Assay for Quantitation of Human Immunodeficiency Virus Type 1 RNA in Plasma: Application to Acute Retroviral Infection," J Clin Microbiol, 32(2):292-300, Feb. 1994.
Pachl et al., "Rapid and Precise Quantification of HIV-1 RNA in Plasma Using a Branched DNA Signal Amplification Assay," J Acquired Immune Deficiency Syndromes and Human Retrovirology, 8:446-454, 1995.
Peabody and Ely, "Control of Translational Repression by Protein--Protein Interactions," Nuc Acids Res, 20(7):1649-1655, 1992.
Peabody and Lim, "Complementation of RNA Binding Site Mutations in MS2 Coat Protein Heterodimers," Nuc Acids Res, 24(12):2352-2359, 1996.
Peabody, "Translational Repression by Bacteriophage MS2 Coat Protein Expressed from a Plasmid," J Biol Chem, 265(10):5684-5689, Apr. 1990.
Piatak et al., "Quantitative Competitive Polymerase Chain Reaction for Accurate Quantitation of HIV DNA and RNA Species," Biotechniques, 14(1):70-79, 1993.
Pickett and Peabody, "Encapsidation of Heterologous RNAs by Bacteriophage MS2 Coat Protein," Nuc Acids Res, 21(19):4621-4626, 1993.
Pushko et al., "Analysis of RNA Phage fr Coat Protein Assembly by Insertion, Deletion and Substitution Mutagenesis," Protein Engineering, 6(8):883-891, 1993.
Qiao et al., "Interference with Bacteriophage .phi.6 Genomic RNA Packaging by Hairpin Structures," J Virology, 69(9):5502-5505, Sep. 1995.
Schneeberger and Zeillinger, "PCR-Mediated Synthesis of Exogenous Competitors for Quantitative RT-PCR," Biotechniques, 20(3):360-361, 1996.
Shaklee et al., "Infectious Positive- and Negative-Strand Transcript RNAs from Bacteriophage Q.beta. cDNA Clone," Virology, 163:209-213, 1988.
Shaklee, "Negative-Strand RNA Replication by Q.beta. and MS2 Positive-Strand RNA Phage Replicases," Virology, 178:340-343, 1990.
Shiba and Saigo, "Packaging of tRNA and 6 S Stable RNA into Bacteriophage MS2 Particles Produced in Escherichia coli Treated with 5-Fluorouracil," Virology, 119:209-213, 1982.
Shiba and Suzuki, "Localization of a Protein in the RNA-A Protein Complex of RNA Phage MS2," Biochimica et Biophysica Acta, 654:249-255, 1981.
Stockley et al., "Molecular Mechanism of RNA Phage Morphogenesis," Int. J. Biochem., 26(10/11)1249-1260, 1994.
Stockley et al., "Probing Sequence-Specific RNA Recognition by the Bacteriophage MS2 Coat Protein," Nuc Acids Res, 23(13):2512-2518, 1995.
Valegard et al., "Crystal Structure of an RNA Bacteriophage Coat Protein-Operator Complex," Nature, 371:623-626, Oct. 1994.
Valegard et al., "The Three-dimensional Structure of the Bacterial Virus MS2," Nature, 345:36-41, May 1990.
van Gemen, "A One-Tube Quantitative HIV-1 RNA NASBA Nucleic Acid Amplification Assay Using Electrochemiluminescent (ECL) Labelled Probes," J Viorological Methods, 49:157-168, 1994.
Witherell et al., "Specific Interaction Between RNA Phage Coat Proteins and RNA," Proc Nuc Acid Res Molec Biol, 40:185-220, 1991.
Witherell et al., "Cooperative Binding of R17 Coat Protein to RNA," Biochem, 29:11051-11057, 1990.
Young et al., "Detection of Hepatitis C Virus RNA by a Combined Reverse Transcription-Polymerase Chain Reaction Essay," J Clinical Microbiol, 31(4):882-886, Apr. 1993.
Dolja et al., "Phylogeny of Capsid Proteins of Rod-Shaped and Filamentous RNA Plant Viruses: Two Families with Distinct Patterns of Sequence and Probably Structure Conservation," Virology, 184:79-86, 1991.
Duda et al., "Expression of Plasmid-Encoded Structural Proteins Permits Engineering of Bacteriophage T4 Assembly," Virology, 179:728-737, 1990.
Durham, "Structures and Roles of the Polymorphic Forms of Tobacco Mosaic Virus Protein," J. Mol. Biol., 67:289-305, 1972.
Durham, "The Cause of Irreversible Polymerisation of Tobacco Mosaic Virus Protein," FEBS Letters, 25(1):147-152, 1972.
Fritsch et al., "Specificity of TMV RNA Encapsidation: in vitro Coating of Heterologous RNA by TMV Protein," Virology, 56:33-45, 1973.
Gal-On et a

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Ribonuclease resistant RNA preparation and utilization does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Ribonuclease resistant RNA preparation and utilization, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ribonuclease resistant RNA preparation and utilization will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-314177

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.