Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-12-01
1996-04-09
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
540145, A61K 3140, C07D48722
Patent
active
055062555
ABSTRACT:
Novel photosensitizers related to rhodoporphyrins and phylloerythrin methyl ester, their preparation and use as photosensitizers for detection and treatment of tumors by photodynamic therapy. The novel photosensitizers accumulate and concentrate preferentially in tumor tissue, have strong light absorption in the 650 to 700 nm region and have reduced skin phototoxicity.
REFERENCES:
patent: 4920143 (1990-04-01), Levy et al.
patent: 5087636 (1992-02-01), Jamieson et al.
patent: 5095030 (1992-03-01), Levy et al.
patent: 5171749 (1992-12-01), Levy et al.
patent: 5238940 (1993-08-01), Liu et al.
patent: 5283255 (1994-02-01), Levy et al.
patent: 5354858 (1994-10-01), Morgan et al.
Pandey et al, Chemical Abstracts, vol. 121 (1993) 108319.
Smith, Kevin, M., et al., "Meso Substitution of Chlorophyll Derivatives: Direct Route for Transformation of Bacteriopheophorbides d into Bacteriopheophorbides c", The American Chemical Society, 107, 4946-4954, (1985).
Meunier, Isabelle, et al., "New Syntheses of Benzoporphyrin Derivatives and Analogues for Use in Photodynamic Therapy", Bioorganic & Medical Chemistry Letters, vol. 2, No. 22, pp. 1575-1580, (1992).
Pandey, Ravindra, K., et al., "Efficient Synthesis of new Classes of Regiochemically Pure Benzoporphyrin Derivatives", Bioorganic & Medicinal Chemistry Letters, vol. 3, No. 12, pp. 2615-2618, (1993).
Meunier, Isabelle, et al., "Benzoporphyrin Derivatives: Synthesis, Structure and Preliminary Biological Activity", J. Chem. Soc. Perkin Trans., pp. 961-969, (1994).
Callott, Henry, J., et al., "Additions to Porphins involving the Formation of New Carbon-Carbon Bonds", J. Chem. Soc. Perkin Trans. I, 1424 (1973).
Dougherty Thomas J.
Jagerovic Nadine
Pandey Ravindra K.
Ryan Joseph M.
Smith Kevin M.
Raymond Richard L.
The Regents of the University of California
Verny Hana
LandOfFree
Rhodoporphyrin and phylloerythrin related photosensitizers for p does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Rhodoporphyrin and phylloerythrin related photosensitizers for p, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Rhodoporphyrin and phylloerythrin related photosensitizers for p will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-139415