Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Reexamination Certificate
2007-10-30
2007-10-30
Prouty, Rebecca E. (Department: 1652)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
C435S129000, C435S069100, C435S252200, C435S471000, C435S320100, C435S252300, C435S252330, C536S023200
Reexamination Certificate
active
11083327
ABSTRACT:
The invention relates to aRhodococcuspolynucleotide cluster which contains nucleotide sequences which encode polypeptides having the activity of a nitrile hydratase, of an auxiliary protein P15K which activates this enzyme and of a cobalt transporter, to transformed microorganisms in which the nucleotide sequences encoding these proteins are present in increased quantity, and to the use of the transformed microorganisms for preparing amides from nitriles.
REFERENCES:
patent: 5807730 (1998-09-01), Ito et al.
patent: 2004/0142447 (2004-07-01), Robins et al.
patent: 101 55 928 (2001-11-01), None
patent: 0 362 829 (1995-07-01), None
patent: 0 790 310 (1997-08-01), None
patent: 1 055 724 (2000-11-01), None
patent: 5-284982 (1993-11-01), None
patent: WO/98/32872 (1998-07-01), None
patent: WO 01/60789 (2001-08-01), None
patent: WO 02/055670 (2002-07-01), None
patent: WO 02/070717 (2002-09-01), None
Shimizu et al. Accession No. E 13809, (JP 1997234075, Sep. 9, 1997).
Brady, et al., “Characterisation of Nitrilase and Nitrile Hydratase Biocatalytic Systems,”Appl. Microbiol. Biotechnol. 64:76-85 (2004).
Ingvorsen, et al., “Microbial Hydrolysis of Organic Nitriles and Amides,”CIBA Foundation Symposium 140:16-31 (1988).
Lee, “High Cell-Density Culture ofEscherichia coli,”TIBECH 14:98-105 (1996).
Kobayashi, et al., “Cobalt Proteins,”Eur. J. Biochem. 261:1-9 (1999).
Kobayashi, et al., “Enzymatic Synthesis of Acrylamide: A Success Story Not Yet Over,”TIBECH 10:402-408 (1992).
Komeda, et al., “A Novel Transporter Involved in Cobalt Uptake,”Proc. Natl. Acad. Sci. USA 94:36-41 (1997).
Martinkova, et al., “Synthetic Applications of Nitrile-Converting Enzymes,”Curr. Org. Chem. 7:1279-1295 (2003).
Nojiri, et al., “Functional Expression of Nitrile Hydratase inEscherichia coli: Requirement of a Nitrile Hydratase Activator and Post-Translational Modification of a Ligand Cysteine,”J. Biochem. 125:696-704 (1999).
Riesenberg, et al., “High-Cell Density Cultivation of Microorganisms,”Appl. Microbiol. Biotechnol. 51:422-430 (1999).
Wu, et al., “Over-Production of Stereoselective Nitrile Hydratase fromPseudomonas putida5B inEscherichia coli: Activity Requires a Novel Downstream Protein,”App. Microbiol. Biotechnol. 48:704-708 (1997).
English Language Abstract for Reference B3 above—WO 02/055670.
English Language Abstract for Reference B above—DE 101 55 928.
English Language Abstract for Reference B9 above—JP 5-284982.
Binder Michael
Deiting Uta
Huthmacher Klaus
Kula Maria-Regina
Odendahl Konrad
Degussa - AG
Law Office of Michael A. Sanzon, LLC
Meah M. Younus
Prouty Rebecca E.
Sanzo Michael A.
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