Rhodococcus equi mutants and vaccines comprising same

Details Rhodococcus equi mutants and vaccines comprising same Rhodococcus equi mutants and vaccines comprising same

2007-11-20

2007-11-20

Swartz, Rodney P (Department: 1645)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

C424S009100, C424S009200, C424S184100, C424S234100, C435S243000, C435S252100, C435S252300, C435S320100, C435S440000, C435S470000, C435S471000, C536S023100

Reexamination Certificate

active

11036797

ABSTRACT:
Mutant strains ofRhodococcus equiare disclosed, and vaccines comprising same.

REFERENCES:
Hondalus and Mosser; “Survival and Replication ofRhodococcus equiin Macrophages”; 1994;Infection and Immunity; 62(10): 4167-4175.
Hondalus; “Pathogenesis and virulence ofRhodococcus equi”; 1997;Veterinary Microbiology; 56: 257-268.
Giguere, et al.; “Role of the 85-Kilobase Plasmid and Plasmid-Encoded Virulence-Associated Protein A in Intracellular Survival and Virulence ofRhodococcus equi”; 1999;Infection and Immunity; 67(7): 3548-3557.
Darrah, et al.; “Cooperation between Reactive Oxygen and Nitrogen Intermediates in Killing ofRhodococcus equiby Activated Macrophages”; 2000;Infection and Immunity; 68(6): 3587-3593.
International Search Report for PCT/US003/22101 dated Mar. 9, 2004.

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