Rhodanines useful as a therapeutic agent for diabetic complicati

Details Rhodanines useful as a therapeutic agent for diabetic complicati Rhodanines useful as a therapeutic agent for diabetic complicati

1984-11-28

1986-09-02

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

514369, C07D27736, A61K 31425

Patent

active

046097368

ABSTRACT:
A rhodanine derivative having the following general formula (I): ##STR1## wherein R is an acyclic alkyl group having 2 to 10 carbon atoms which may be substituted by a halogen atom or an acyclic alkenyl group having 2 to 19 carbon atoms which may be substituted by a halogen atom; or a nontoxic salt thereof. The rhodanine derivative has potent platelet aggregation inhibiting activity and aldose reductase inhibiting activity and therefore is useful as a therapeutic agent for diabetic complications.

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