Rho-kinase inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S275000, C544S253000, C544S323000, C544S324000, C544S325000

Reexamination Certificate

active

06943172

ABSTRACT:
Disclosed are compounds and derivatives thereof, their synthesis, and their use as Rho-kinase inhibitors. These compounds are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.

REFERENCES:
patent: 4642347 (1987-02-01), Kreft, III et al.
patent: 4952567 (1990-08-01), DeMeyts et al.
patent: 5240940 (1993-08-01), Arnold et al.
patent: 5245036 (1993-09-01), Robey et al.
patent: 5324839 (1994-06-01), Clemence et al.
patent: 5478938 (1995-12-01), Clemence et al.
patent: 5817674 (1998-10-01), Clemence et al.
patent: 5840695 (1998-11-01), Frank et al.
patent: 5885803 (1999-03-01), Bandman et al.
patent: 5906819 (1999-05-01), Kaibuchi et al.
patent: 5932470 (1999-08-01), Frank et al.
patent: 5958944 (1999-09-01), Arita et al.
patent: 5972598 (1999-10-01), Chaudhary et al.
patent: 5977102 (1999-11-01), Himmelsbach et al.
patent: 6004979 (1999-12-01), Clemence et al.
patent: 6153617 (2000-11-01), Bridges
patent: 6184226 (2001-02-01), Chakravarty et al.
patent: 6207148 (2001-03-01), Bandman et al.
patent: 6218410 (2001-04-01), Uehata et al.
patent: 6277989 (2001-08-01), Chakravarty et al.
patent: 6326373 (2001-12-01), Uckun et al.
patent: 6391874 (2002-05-01), Cockerill et al.
patent: 2001/0014679 (2001-08-01), Tang et al.
patent: 2001/0044442 (2001-11-01), Uckun et al.
patent: 2002/0055514 (2002-05-01), Uckun et al.
patent: 1 034 793 (2000-09-01), None
patent: 1 163 910 (2001-12-01), None
patent: 1 174 150 (2002-01-01), None
patent: 1 177 796 (2002-02-01), None
patent: WO 96/40142 (1996-12-01), None
patent: WO 97/03069 (1997-01-01), None
patent: WO 98/02434 (1998-01-01), None
patent: WO 98/02438 (1998-01-01), None
patent: WO 99/23113 (1999-05-01), None
patent: WO 99/24440 (1999-05-01), None
patent: WO 99/35132 (1999-07-01), None
patent: WO 99/35146 (1999-07-01), None
patent: WO 99/65908 (1999-12-01), None
patent: WO 00/12497 (2000-03-01), None
patent: WO 00/13497 (2000-03-01), None
patent: WO 00/39101 (2000-07-01), None
patent: WO 00/55162 (2000-09-01), None
patent: WO 00/57914 (2000-10-01), None
patent: WO 01/09134 (2001-02-01), None
patent: WO 01/28561 (2001-04-01), None
patent: WO 02/24667 (2002-03-01), None
patent: WO 02/30465 (2002-04-01), None
patent: WO 02/053143 (2002-07-01), None
Blackburn et al., Chemical Abstracts, vol. 138:321291, 2003.
Gour et al., Chemical Abstracts, vol. 137:363033, 2002.
Chemical Abstract No. 117:251318p “Novel piperazinyl-substituted pyrimidines as antihypertensive and vasodilators” (1993).
English Abstract of WO 95/28387 (US 5,598,994), 1995.
English Abstract of WO00/57914, 2000.

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