Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-01-11
1988-12-13
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548235, 548236, A61K 3142, C07D49322
Patent
active
047911280
ABSTRACT:
Acylated derivatives of rhizoxin and of rhizoxin-2-ene may be prepared by reacting rhizoxin or rhizoxin-2-ene with an acid or reactive derivative thereof. They have excellent anti-tumor activity.
REFERENCES:
Abstract of the Proceedings of the Cancer Society, Oct., 1984.
Paper sheets for "Poster Session" International Chemical Congress of the Pacific Basin Society Dec. 18, 1984, Honolulu, Hawaii.
The Merck Index, Tenth Edition, 1983, 9650, Undecylenic Acid.
National Inst. of Agro-Environmental Sciences, CA 103-1061576.
Iwasaki et al., J. Antibiotics, 37, 354 (1984).
Arakawa Masao
Iwasaki Shigeo
Namikoshi Michio
Okuda Shigenobu
Shimizu Fusaaki
Daus Donald G.
Sankyo Company Limited
Shen Cecilia
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