Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2007-04-24
2007-04-24
Ulm, John (Department: 1649)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S069100, C435S252300, C435S320100, C530S350000, C536S023500
Reexamination Certificate
active
10478534
ABSTRACT:
The present invention identifies the presence of MCH-2R in the dog, ferret and rhesus monkey. MCH-2R is a G-protein coupled receptor that responds to MCH and is distinct from MCH-1R. MCH-2R polypeptide and nucleic acid sequences related to the dog, ferret, and rhesus monkey MCH-2R are described herein along with uses of such polypeptides and nucleic acids.
REFERENCES:
patent: 5264565 (1993-11-01), England et al.
patent: 5480784 (1996-01-01), Kacian et al.
patent: 5686597 (1997-11-01), Coleman et al.
patent: 5852188 (1998-12-01), Cook
patent: 5859221 (1999-01-01), Cook et al.
patent: 6033872 (2000-03-01), Bergsma et al.
patent: 6221613 (2001-04-01), Salon et al.
patent: 6362326 (2002-03-01), Sathe et al.
patent: 6593108 (2003-07-01), Liu et al.
patent: 2003/0114644 (2003-06-01), Kinrade et al.
patent: 2003/0166834 (2003-09-01), Kinrade et al.
patent: 1 033 401 (2000-02-01), None
patent: WO 94/01548 (1994-01-01), None
patent: WO 96/18651 (1996-06-01), None
patent: WO 97/05252 (1997-02-01), None
patent: WO 98/02582 (1998-01-01), None
patent: WO 99/28492 (1999-06-01), None
patent: WO 00/37113 (2000-06-01), None
patent: WO 00/49046 (2000-08-01), None
patent: WO 00/75166 (2000-12-01), None
patent: WO 01/05947 (2001-01-01), None
patent: WO 01/07606 (2001-02-01), None
patent: WO 01/07611 (2001-02-01), None
patent: WO 01/36471 (2001-05-01), None
patent: WO 01/62797 (2001-08-01), None
patent: WO 01/70975 (2001-09-01), None
patent: WO 02/08290 (2002-01-01), None
An, S. et al. “Identification and characterization of a melanin-concentrating hormone receptor”, Proc. Natl. Acad. Sci USA, 2001, vol. 98, pp. 7576-7581.
Bachner, D. et al. “Identification of melanin concentrating hormone (MCH) as the natural ligand for the orphan somatostatin-like receptor 1 (SLC-1)”, FEBS Letters, 1999, vol. 457, pp. 522-524.
Bednarek, M. et al. “Short Segment of Human Melanin-Concentrating Hormone That Is Sufficient for Full Activation of Human Melanin-Concentrating Hormone Receptors 1 and 2”, Biochemistry, 2001, vol. 40, pp. 9379-9386.
Bork, P. et al. “Go hunting in sequence databases but watch out for traps”, Trends in Genetics, 1996, vol. 12, pp. 425-427.
Bork, P. “Powers and Pitfalls in Sequence Analysis: The 70% Hurdle”, Genome Research, 2000, vol. 10, pp. 398-400.
Brenner, S. “Errors in genome annotation”, Trends in Genetics, 1999, vol. 15, pp. 132-133.
Breton, C. et al. “Isolation and characterization of the human melanin-concentrating hormone gene and a variant gene”, Molecular Brain Research, 1993, vol. 18, pp. 297-310.
Chambers, J. et al. “Melanin-concentrating hormone is the cognate ligand for the orphan G-protein-coupled receptor SLC-1”, Nature, 1999, vol. 400, pp. 261-265.
Doerks, T. et al. “Protein annotation: detective work for function prediction”, Trends in Genetics, 1998, vol. 14, pp. 248-250.
Erickson, J. et al., “Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y”, Nature, 1996, vol. 381, pp. 415-418.
Flier, J. et al. “Obesity and the Hypothalamus: Novel Peptides for New Pathways”, Cell, 1998, vol. 92, pp. 437-440.
Hill, J. et al. “Molecular Cloning and Functional Characterization of MCH2, a Novel Human MCH Receptor”, The Journal of Biological Chemistry, 2001, vol. 276, pp. 20125-20129.
Knigge, K. et al. “Melanotropic Peptides in the Mammalian Brain: The Melanin-Concentrating Hormone”, Peptides, 1996, vol. 17, pp. 1063-1073.
Lakaye, B. et al. “Cloning of the rat brain cDNA encoding for the SLC-1 G protein-coupled receptor reveals the presence of an intron in the gene”, Biochimica et Biophysica Acta, 1998, vol. 1401, pp. 216-220.
Lembo, P. et al. “The receptor for the orexigenic peptide melanin-concentrating hormone is a G-protein-coupled receptor”, Nature Cell Biology, 1999, vol. 1, pp. 267-271.
Ludwig, D. et al. “Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance”, The Journal of Clinical Investment, 2001, vol. 107, pp. 379-386.
Mahairas, G. et al., “Sequence-tagged connectors: A sequence approach to mapping and scanning the human genome”, Proc. Natl. Acad. Sci. USA, 1999, vol. 96, pp. 9739-9744.
Mori, M. et al. “Cloning of a Novel G Protein-Coupled Receptor, SLT, a Subtype of the Melanin-Concentrating Hormone Receptor”, Biochemical and Biophysical Research Communications, 2001, vol. 283, pp. 1013-1018.
Nahon, J. “The Melanin-Concentrating Hormone: From the Peptide to the Gene”, Critical Reviews in Neurobiology, 1994, vol. 8, pp. 221-262.
Ngo, J. et al. “Computational Complexity, Protein Structure Prediction, and the Levinthal Paradox” inThe Protein Folding Problem and Tertiary Structure Prediction, edited by K. Merz and S. L. Grand, Chapter 14, pp. 492-495, Birkhäuser, Boston (1994).
Pearson, W. “Rapid and Sensitive Sequence Comparison with FASTP and FASTA”, Methods in Enzymology, 1990, vol. 183, pp. 63-98.
Qu, D. et al. “A role for melanin-concentrating hormone in the central regulation of feeding behaviour”, Nature, 1996, vol. 380, pp. 243-247.
Rodriguez, M. et al. “Cloning and Molecular Characterization of the Novel Human Melanin-Concentrating Hormone Receptor MCH2”, Molecular Pharmacology, 2001, vol. 60, pp. 632-639.
Sailer, A. et al. “Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R”, Proc. Natl. Acad. Sci. USA, 2001, vol. 98, pp. 7564-7569.
Saito, Y. et al. “Molecular characterization of the melanin-concentrating-hormone receptor”, Nature, 1999, vol. 400, pp. 265-269.
Shimada, M. et al. “Mice lacking melanin-concentrating hormone are hypophagic and lean”, Nature, 1998, vol. 396, pp. 670-674.
Shimomura, Y. et al. “Isolation and Identification of Melanin-Concentrating Hormone as the Endogenous Ligand of the SLC-1 Receptor”, Biochemical and Biophysical Research Communications, 1999, vol. 261, pp. 622-626.
Skolnick, J. et al. “From genes to protein structure and function: novel applications of computational approaches in the genomic era”, Trends in Biotechnology, 2000, vol. 18, pp. 34-39.
Smith, T. et al. The challenges of genome sequence annotation or “The devil is in details”, Nature Biotechnology, 1997, vol. 15, pp. 1222-1223.
Tan, C. et al. “Melanin-Concentrating Hormone Receptor Subtypes 1 and 2: Species-Specific Gene Expression”, Genomics, 2002, vol. 79, pp. 785-792.
Wells, J. et al. “Addititivy of Mutational Effects in Proteins”, Biochemistry, 1990, vol. 29, pp. 8509-8517.
Database WPI, Section Ch, Week 200173, Derwent Publications Ltd., London, GB; AN 2001-639126 & WO 01/70975 A (Yamanouchi Pharmaceutical Company, Ltd.), Sep. 27, 2001.
Database WPI, Section Ch, Week 200049, Derwent Publications Ltd., London, GB; AN 2000-543749, & WO 01/49046 A (Takeda Chemical Industries, Ltd.), Aug. 24, 2000.
Geneseq Entry Concerning EP 1 033 401 A2, Oct. 6, 2000.
GenBank Accession No. H04706, Jun. 20, 1995.
GenBank Accession No. AQ190629, Nov. 4, 1998.
GenBank Accession No. AQ747249, Juy 19, 1999.
Sano Hideki
Tan Carina
Banyu Pharmaceutical Co. Ltd.
Heber Sheldon O.
Merck & Co. , Inc.
Ulm John
LandOfFree
Rhesus monkey, dog and ferret melanin-concentrating hormone... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Rhesus monkey, dog and ferret melanin-concentrating hormone..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Rhesus monkey, dog and ferret melanin-concentrating hormone... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3737166