Rheologically modified and osmotically balanced fill material fo

Details Rheologically modified and osmotically balanced fill material fo Rheologically modified and osmotically balanced fill material fo

1997-08-29

1999-12-07

Prebilic, Paul B.

Prosthesis (i.e., artificial body members), parts thereof, or ai

Breast prosthesis

Implantable

623 7, 623 11, 623 66, A61F 212

Patent

active

059975741

ABSTRACT:
A rheologically modified, osmotically balanced dispersion for an implant for the body. The dispersion includes an osmotic control agent of preferably polyvinylpyrrolidinone, a rheological agent of preferably guar gum, and an antimicrobial. Methods for filling an implant are also disclosed. The osmotic control agent or first polymeric agent is present in the dispersion in an amount effective to substantially balance the osmotic pressure of the implant with the osmotic pressure of the portion of the body into which it is implanted. The rheological agent or second polymeric agent forms a three-dimensional network and is present in the dispersion in an amount effective such that the fill material is pseudoplastic. Both the first and second polymeric agents are biocompatible.

REFERENCES:
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patent: 5658329 (1997-08-01), Purkait
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Excerpt from U.S. Patent 4,780,543 which sets forth the molecular weight range of agar Oct. 1988.

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