Rh blood group antigen compositions and methods of use

Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Means for analyzing liquid or solid sample

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C422S051000, C435S004000, C435S007100, C435S091500, C435S337000, C435S344100, C436S518000, C436S520000, C436S523000

Reexamination Certificate

active

06911178

ABSTRACT:
Disclosed are novel protein and peptide compositions comprising soluble and bound forms of immunologically-active blood group antigens including mammalian Rh antigens. In preferred embodiments methods for the isolation and purification of serologically-active human Rh antigens such as D, c, C, E, and e are disclosed. Also disclosed are methods for the adsorption of immunologically-active Rh antigens to solid supports. Diagnostic kits, methods, and devices for the detection of Rh antibodies in clinical and non-clinical samples are also disclosed. Devices, compositions and methods for the isolation, purification and quantitation of anti-Rh antibodies from solution are also provided.

REFERENCES:
patent: 5068191 (1991-11-01), Clausen et al.
patent: 5087338 (1992-02-01), Perry et al.
patent: 5387511 (1995-02-01), Davidson et al.
patent: 5773222 (1998-06-01), Scott
patent: 5840585 (1998-11-01), Rodkey et al.
patent: 242716 (1987-02-01), None
patent: WO 90/13032 (1990-11-01), None
Xia et al. Kinetics of specific and nonspecific adhesion of red blood cellls on glagg Biophysical Journal (1993) 65: 1073-1083.
Agre and Cartron, “Molecular Biology of the Rh Antigens,”Blood, 78:551-563, 1991.
Carter, “Preliminary Report on a Substance Which Inhibits Anti-Rh Serum,”Am. J. Clin. Path., 17:646-649, 1947.
Carter, “Rh Hapten: Its Preparation, Assay and Nature,”J. Immunol., 61:79-88, 1949.
Carter, “Preparation and Assay of a Red Cell Fraction of the Rh Factor,”Am. J. Clin. Path., 21:561-565, 1951.
Carter, “The Results in Clinical Use of Rh Hapten,”Am. J. Ob. Gyn., 102:447-450, 1968.
Carter et al., “Evaluation of Rh Hapten,”Am. J. Ob. Gyn., 72:655-659, 1956.
Carter and Lewis, “The Effects of Orally Administered Rh Hapten. A Study of 17 Cases,”Am. J. Ob. Gyn., 76:1286-1287, 1958.
Iyer et al., “Distribution of IgG Subtypes in Maternal Anti-D Sera and Their Prognostic Value in Rh Haemolytic Disease of the New-Born,”Acta Haematol., 88::78-81, 1992.
Masouredis, “Quantitative Studies of the Rho(D) Antigenic Determinants on Gorilla Erythrocytes,”Transfusion11(5):270-280, 1971.
Moore et al., “Isolation of Membrane Components Associated with Human Red Cell Antigens Rh(D), (c), (E) and Fya,”Nature, 295:529-531, 1982.
Moore et al. , “Evaluation of monoclonal anti-Rh antibodies as reagents for blood grouping and for the identification of red cell membrane components associated with Rh antigen activity,”Revue Française de Transfusion et Immuno-hématologie, 31(2):141-144, 1988.
Paradis et al., “Protective Effect of the Membrane Skeleton on the Immunologic Reactivity of the Human Red Cell Rho(D) Antigen,”J. Immunol., 137:240-244, 1986.
Plapp et al., “Partial Purification of Rh(D) Antigen from Rh Positive and Negative Erythrocytes,”Proc. Natl. Acad. Sci. USA, 76:2964-2968, 1979.
Yokoi et al. “Isolation and Purification of Rho(D) Antigen of Human Erythrocyte Membrane and Its Serological Property,”J. Exp. Med., 141:143-154, 1983.
Foreign Search Report dated Dec. 2, 1997.
Oellerich M., “Enzyme-Immunoassay: A Review,”J. Clin. Chem. Clin. Biochem, 22:895-904, 1984.
Sambrook, J. et al. “Molecular Cloning A Laboratory Manual,” Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press, Second Edition, pp. 18.16-18.18, 1989.
Suyama et al. “Antibody produced against isolated Rh(D) polypeptide reacts with other Rh-related antigens',” Chemical Abstracts, vol. 109, Abstract No. 228190,Blood, 72(5):1622-1626, 1988.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Rh blood group antigen compositions and methods of use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Rh blood group antigen compositions and methods of use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Rh blood group antigen compositions and methods of use will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3482192

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.