RFRP-3 and DNA thereof

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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Details

C530S350000, C435S069100

Reexamination Certificate

active

11223294

ABSTRACT:
The RFRP-3 peptide of the present invention which is an agent for promoting prolactin secretion is useful as a prophylactic and/or therapeutic agent for various diseases associated with prolactin secretion, such as hypoovarianism, seminal vesicle hypoplasia, menopausal syndrome and hypothyroidism.

REFERENCES:
patent: WO 00/29441 (2000-05-01), None
patent: WO 01/66134 (2001-09-01), None
patent: WO 02/46405 (2002-06-01), None
S. Hinuma, et al., “New Neuropeptides Containing Carboxy-terminal RFamide and their Receptor in Mammals”, Nature Cell Biology, (2000), pp. 703-708, vol. 2.
Q. Liu, et al., “Identification and Characterization of Novel Mammalian Neuropeptide FF-like Peptides that Attenuate Morphine-induced Antinociception”, The Journal of Biological Chemistry, (2001), pp. 36961-36969, vol. 276, No. 40.

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