Reversing excitotoxic CNS damage by cellular implantation

Details Reversing excitotoxic CNS damage by cellular implantation Reversing excitotoxic CNS damage by cellular implantation

1995-07-31

1999-08-10

Witz, Jean C.

Drug, bio-affecting and body treating compositions

Extract, body fluid, or cellular material of undetermined...

Endocrine system, other than the thymus gland

424 937, A61K 3555

Patent

active

059356065

ABSTRACT:
The use of certain types of CNS transplants in preventing and reversing excitotoxic CNS damage.

REFERENCES:
patent: 4806543 (1989-02-01), Choi
patent: 4883666 (1989-11-01), Sabel et al.
patent: 5093525 (1992-03-01), Weber et al.
Siegan et al., Brain Research 680(1-2): 88-98 (May 22, 1995).
The Merck Manual of Diagnosis and Therapy, 1990 pp. 1404, 1495, 1513.
Backlund et al. 1985. Transplantation of Adrenal Medullary Tissue to Striatum in Parkinsonism. In: Neural Grafting in the Mammalian CNS (Bjorklund and Stenevi, eds.). Elsevier Science Publishers pp. 551-556.
Sagen et al. 1986 Adrenal Medullary Tissue Transplants in the Rat Spinal Cord Reduce Pain Sensitivity. Brain Research; 384. pp. 189-184.
Freed et al. 1981 Transplanted adrenal chromaffin cells in rat brain reduce lesian-induced rotational behavior Nature: 292. pp. 351-352.
Patel et al. 1995. Pharmacotherapy of Cognitive Impairment in Alzheimer's Disease: A review. Journal of Geriatric Psychiatry and Neurology: 8 pp. 81-95.

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