Drug – bio-affecting and body treating compositions – Topical body preparation containing solid synthetic organic... – Ophthalmic preparation
Patent
1994-08-09
1997-02-04
Azpuru, Carlos
Drug, bio-affecting and body treating compositions
Topical body preparation containing solid synthetic organic...
Ophthalmic preparation
424427, 424428, 514912, 514913, 514914, 514915, A61K 3174, A61K 3119, A61K 4738, A01N 2504
Patent
active
055995349
ABSTRACT:
Reversibly gel-forming compositions for sustained delivery of bio-affecting substances are disclosed. The compositions exhibit significant changes in viscosity in response to changes in pH. The compositions contain relatively low concentrations of a stable combination of at least one pH-responsive gelling polymer and at least one other thermally nonresponsive polymer. The compositions are preferably formulated to include one or more therapeutic or diagnostic agents for administration as a liquid that will gel in situ or for topical application as a pre-formed gel.
REFERENCES:
patent: 4188373 (1980-02-01), Krezanoski et al.
patent: 4271143 (1981-06-01), Schoenwald et al.
patent: 4407792 (1983-10-01), Schoenwald et al.
patent: 4474751 (1984-10-01), Haslam et al.
patent: 4474752 (1984-10-01), Haslam et al.
patent: 4474753 (1984-10-01), Haslam et al.
patent: 5252318 (1993-10-01), Joshi et al.
patent: 5292516 (1994-03-01), Viegas et al.
patent: 5292517 (1994-03-01), Chang et al.
Podder et al., (1992), Exp. Eye Res., 54: 747-757.
Schoenwald et al., (1978) J. Pharm. Sci., 67: 1280-1283.
Baustian Cara L.
Himmelstein Kenneth J.
Azpuru Carlos
University of Nebraska
LandOfFree
Reversible gel-forming composition for sustained delivery of bio does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Reversible gel-forming composition for sustained delivery of bio, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Reversible gel-forming composition for sustained delivery of bio will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-676050