Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1996-06-03
2000-02-29
Celsa, Bennett
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 16, 514 17, 514 18, 514 19, 514 37, 530328, 530329, 530330, 530331, 435 4, 435 23, 435 24, 435 9463, 435 9465, 435212, 544121, 564511, A61K 3800, C07K 200
Patent
active
060309466
ABSTRACT:
Cysteine protease inhibitors are provided.
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Hara, K., et al. "Inhibition of Calcium-Activated Neutral Protease of Monkey Cardiac Muscle by Epoxysuccinic Acid Derivatives," Biomedical Research, 4(1):121-124 (1983).
Westmark et al., "Photoregulation of Enzyme Activity. Photochromic, Transition-State-Analogue Inhibitors of Cysteine and Serine Proteases," J. Am. Chem. Soc., 115:3416-3419 (1993).
Turk et al., "The Cystatins: Protein Inhibitors of Cysteine Proteinases," FEBS, 285(2):213-219 (1991).
Giordano et al., "Synthesis and Properties of D-glucosamine N-peptidyl Derivatives as Substrate Analog Inhibitors of Papain and Cathepsin B," Eur. J. Med. Chem. 26:753:762 (1991).
Klaus Jeffrey L.
Kuo Elaine Yee-Lin
Palmer James T.
Rasnick David
AxyS Pharmaceuticals, Inc.
Brezner David J.
Celsa Bennett
Silva Robin M.
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