Reversible attachment of a membrane active polymer to a...

Details Reversible attachment of a membrane active polymer to a... Reversible attachment of a membrane active polymer to a...

2004-02-17

2010-10-19

Epps-Smith, Janet L (Department: 1633)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C424S450000, C435S325000, C435S375000, C435S455000

Reexamination Certificate

active

07816337

ABSTRACT:
Described is a process for delivering a biologically active compound to a cell by reversibly linking the compound to a membrane active polymer. In particular, polymer-polynucleotide conjugates are described. Methods for reversibly modifying the polymers to decrease cellular toxicity and improve efficacy are provided.

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WO document is too voluminous, see US Patent Application US20040249122.

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