Reverse loading of liposomes

Details Reverse loading of liposomes Reverse loading of liposomes

1991-01-29

1992-04-14

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

424 11, 4284022, 264 41, 264 43, 264 46, A61K 3722

Patent

active

051046610

ABSTRACT:
The first part explains the discovery, and means to employ the discovery that whole, intact vesicles and liposomes are not the sole means of burden (drug) delivery by targeting molecules. The second part teaches the discovery of reverse loading of vesicles and liposomes to obtain fully functional core volume load of a useful burden without the trauma degradation of the active burden material, and with greatly extended shelf life.

REFERENCES:
patent: 4448765 (1984-05-01), Ash et al.
patent: 4483929 (1984-11-01), Szoka
patent: 4603044 (1986-07-01), Geho et al.
patent: 4708861 (1987-11-01), Popescu et al.
patent: 4839175 (1989-06-01), Guo et al.
patent: 4880635 (1989-11-01), Janoff et al.
patent: 4885172 (1989-12-01), Bally et al.
patent: 4946683 (1980-08-01), Forssen

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