Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1984-01-11
1986-02-04
Schain, Howard E.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
260112B, 424 99, 424100, 424 85, 424 88, 435226, 514 21, C01G 700, A61K 3724, A61K 3522
Patent
active
045684880
ABSTRACT:
One aspect of the present invention relates to a method for the purification of a protein component of a biological fluid, said method comprising: raising antibodies to impurities commonly present in crude preparations of said components; preparing an immunoadsorbent complex by linking said antibodies to a solid adsorbent suitable for use in column chromatography; processing a preparation of said component containing impurities through a chromatography column containing said immunoadsorbent, thereby causing selective adsorption of said impurities and exclusion of said component in the effluent; and recovering said purified component from said effluent. Another aspect of this invention is directed to human urinary erythropoietin purified by the above method.
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