Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-04-12
2005-04-12
Riley, Jezia (Department: 1637)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S411000, C514S415000, C514S279000, C514S280000
Reexamination Certificate
active
06878737
ABSTRACT:
The present invention describes the use of fumitremorgin A, B and C and a series of diketopiperazines of Formula (I) to resensitize multidrug resistant (MDR) cancer cells to the cytotoxic effects of chemotherapeutic drugs.
REFERENCES:
patent: 5387685 (1995-02-01), Powell et al.
Cole, R.J., and Cox, R.H., Tremorgen Group, in Handbook of Toxic Fungal Metabolites, 1981, Academic Press, New York, 355-367.
Durr, E E et al. Cancer Treat. Rev., 10, 3-11, 1983.
Bhalla, K. et al, Cancer Res., 45, 3657-3662, 1985.
D.M. Harrison et al., Tetrahedron Letters, vol. 27, No. 4, pp. 521-524, 1986.
M. Nakagawa et al., Tetrahedron Letters, vol. 27, No. 28, pp. 3235-3238, 1986.
Batist, G., et al, J.Biol. Chem., 261, 15544-15549, 1986.
R. Plante et al., J. Org. Chem. 1987, 52, 560-564.
Hindenburg, A.A., et al, Cancer Res., 47, 1421-1425, 1987.
Greenberger, L.M., et al, J.Biol.Chem., 262, 13685-13689, 1987.
Gruber, A. et al., Int. J. Cancer, 41, 224-226, 1988.
Kramer, R.A. et al, Science, 24(1), 694-697, 1988.
Dalton, W.S., et al, Cancer Res., 48, 1882-1888, 1988.
S. Kodato et al., Tetrahedron, vol. 44, No. 2, pp. 359-377, 1988.
Young, R.C. Drug resistance; the clinical problem, in Drug Resistance in Cancer Therapy, R.F. Ozols, Editor, Kluwer Acad. Press, Boston, 1-12, 1989.
M. Nakagawa et al., Chem. Pharm. Bull. 37(1), 23-32 (1989).
T. Hino et al., Tetrahedron, vol. 45, No. 7, pp. 1941-1944, 1989.
Goldstein, L.J. et al, J.Natl. Canc. Inst, 81, 116-124, 1989.
Lui, L.F., DNA topoisomerase posions as antitumor drugs, Annu. Rev. Biochem., 58, 351-375, 1989.
Nishiyama, M. and Kuga T., Japan J. Pharmacol., 50, 167-173, 1989.
Cole, S.P.C., et al, Br.J.Cancer, 59, 42-46, 1989.
Harker, W.C. et al, Cancer Res., 49, 4542-4549, 1989.
McGrath, T., et al, Cancer Res., 48, 3959-3963, 1989.
Ford, J.M. et al, Cancer Res., 50, 1748-1756, 1990.
Baas, R. et al, Cancer Res, 50, 5392-5398, 1990.
Ellason, J.F. et al, Int. J. Cancer, 46, 113-117, 1990.
Nishiyama, M. and Kuga T., Japan J. Pharmacol., 52, 201-208, 1990.
Chen, Y.N. et al, J. Biol. Chem., 265, 10073-10080, 1990.
Skehan, P. et al, J. Nat. Cancer Inst., 82, 1107-1112, 1990.
Dietel, M., et al. Cancer Res., 50, 6100-6106, 1990.
Rubinstein, L.V. et al, J. Nat. Cancer Inst., 82, 1113-1117, 1990.
Faulds, D., et al, Drugs, 41, 400-449, 1991.
Cowan, J.D. et al., J.Nat. Canc. Inst., 83, 1077-1084, 1991.
Taylor, C.W. et al, Br.J.Cancer, 63,923-929, 1991.
Harker, W.C. et al, Biochemistry, 30, 9953-9961, 1991.
Nakagawa, M., et al, Cancer Res., 52, 6175-6181, 1992.
Chabner, B.A., Campothecins, J.Clin.Oncol., 10, 3-4, 1992.
Versantvoort, C.H.M., et al, Br.J.Cancer, 68, 939-946, 1993.
Gottesman, M.M. and Pastan, I., Annu. Rev. Biochem, 62, 385-427, 1993.
Arceci, R.J., Blood, 81, 2215-2222, 1993.
Scheper, R.J. et al, Cancer Res., 53, 1475-1479, 1993.
Arceici, R.J. et al., Cancer Res., 53, 310-317, 1993.
Greenberger, L.M., et al., In Vitro Models of Multiple Drug Resistanc and L.J. Goldstein and R.F. Ozols, Editor Kluwer Academic Publishers, Norwell, MA, 69-106, 1994.
Sikic, B.I., et al, J. Clinical Reversal of Multidrug Resistance in Anticancer Drug Resistance, L.J. Goldstein and R.F. Ozols, Editor.
Kluwer Academic Publishers, Norwell, MA 149-165, 1994.
Zhang, X.P., et al, Oncol. Res., 6, 291-301, 1994.
Cole, S.P.C., et al. Cancer Res., 54, 5902-5910, 1994.
Zaman, C.J.R., et al, Proc. Natl. Acad. Sci. USA, 91, 8822-8826, 1994.
Jedlitschky, G. et al, Cancer Res., 54, 4833-4836, 1994.
Futscher, B.W. et al, Biochem. Pharmacol., 47, 1601-1606, 1994.
Flens, M.J. et al, Cancer Res., 54, 4557-4563, 1994.
Leier, I., et al, J. Biol.Chem, 269, 27807-27810, 1994.
Abe, T., et al, Br.J.Cancer, 72, 418-423, 1995.
Tasanki, Y., et al., J. Urology, 154, 1210-1216, 1995.
Gekeler, V., et al, Biochem. Biophs. Res. Commun., 206, 119-126, 1995.
Goldstein, L.J., Current Prob. Cancer, 19, 65-124, 1995.
Brock, I., et al, Cancer Res., 55, 459-462, 1995.
Harker, W.C. et al, Cancer Res., 55, 4962-4971, 1995.
Lois, A.F., et al, Cancer Res., 55, 4010-4013, 1995.
Yang, C.H. et al, Cancer Res., 55, 4004-4009, 1995.
Bow, E.J., J. Clin. Oncol., 14, 1345-1352, 1996.
Tannock, I.F., J. Clin. Oncol., 14, 1756-1764, 1996.
Loe, D.W., et al, European J. Cancer, 32A, 945-957, 1996.
Greenberger, L.M., et al, Oncol. Res., 8, 207-218, 1996.
C.B. Cui et al., Journal of Antibiotics, Jun. 1996.
T. Hino and M. Nakagawa, Heterocycles, vol. 46, 1997.
H. Wang and A. Ganesan, Tetrahedron Letters, vol. 38, No. 24, pp. 4327-4328, 1997.
O'Malley, Gerard J. et al, Tetrahedron Lett. (1987), 28(11), 1131-4.
Bailey, Patrick D., et al, Tetrahedron Lett., (1989), 30(46), 6421-2.
Bailey, Patrick D. et al, J.Chem.Soc., Perkin Trans. 1 (1993), (4), 451-8.
Cui, Cheng-Bin. et al, J. Antibiot. (1996), 49(6), 527-533.
Cui, Cheng-Bin, et al, Tetrahedron (1996), 52(39), 12651-12666.
Cui, Cheng-Bin, et al, Tennen Yuki Kagobutsu Toronkai Koen Yoshishu (1996), 38th, 49-54.
Cui, Cheng-Bin, et al, Tennen Yuki Kagobutsu Toronkai Koen Yoshishu (1996), 38th, 49-54. (English Abstract).
Rabindran, Sridhar K.; Cancer Res. Alert; 2, (2), 19-21, Jul. (2000).
Greenberger Lee Martin
He Haiyin
Rabindran Sridhar Krishna
Moran Daniel B.
Riley Jezia
Wyeth Holdings Corporation
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