Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1997-06-27
1999-06-29
Spivack, Phyllis G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
562508, 562510, A61K 3119, C07C 6232, C07C 6238
Patent
active
059169192
ABSTRACT:
A compound composition and method of treating a retrovirus infection are disclosed. In particular, isolated triterpenes have been shown to have significant inhibitory activity against HIV-1.
REFERENCES:
patent: 4933169 (1990-06-01), Shanbrom
patent: 5086076 (1992-02-01), Herman
patent: 5204324 (1993-04-01), Shanbrom
patent: 5411733 (1995-05-01), Hozumi et al.
patent: 5527890 (1996-06-01), Rao et al.
Serra et al. Pharmacol. Res., 29(4), 359-66 (abstract), 1994.
Konoshima et al., J. Nat. Products, 50(6), 1167-70 (abstract), 1987.
Quere et al., Biochem. Biophys. Res. Commun., 227(2), 484-488, 1996.
Ryu et al., Arch. Pharmacol. Res., 16(4), 339-42 (abstract), 1993.
Brinkworth et al., Biochem. Biophys. Res. Commun., 188: 631-637, 1992.
De-Tommasi, J. Nat. Prod., (Abstract), 55(8):1067-1073, 1992.
Fujioka, T., et al., J. Nat. Prod., 57:243-247, 1994.
Hasegawa et al., Planta. Med., (Abstract), 60(3):240-243, 1994.
Hu, C. Q. et al., J. Nat. Prod., 57:42-51, 1994.
Ito, M. et al., N., Antiviral Res., 7: 127-137, 1987.
Kashiwada et al., J. Med. Chem., 39(5):1016-1017, 1996.
Konoshima et al., J. Nat. Prod., (Abstract) 58(9):1372-1377, 1995.
Li et al., J. Nat. Prod. (Abstract), 56(7):1130-1133, 1993.
McQuade, T.J., et al., Science, 247:454-456, 1990.
Mirmala, M., NUS term finds possible link to AIDS cure, "New Straits Time", Jun. 25, 1996.
Pengsuparp et al., J. Nat. Prod. (Abstract), 58(7):1024-1031, 1995.
Piacente, S. et al., J. Nat. Prod., 59:565-569, 1996.
Seelmeier, S. et al., Proc. Natl. Acad. Sci. USA, 85:6612-6616, 1988.
Shigenaga, S., et al., Phytochemistry, 24:115-118, 1985.
Soler et al., J. Med. Chem, 39(5):1069-1083, 1996.
Wang, S.N. et al., J. Med. Chem. 39: 2047-, 1996.
Xu, H. X., et al., Heterocycles, 38: 167-175, 1994.
Xu, H.X. et al., Phyto. Res., 10:207-210, 1996.
Xu, H.X. et al., J. Nat. Prod. 59(7):643-645, 1996.
Yoshida, T., et al., Chem. Pharm. Bull., 30:4245-4248, 1982.
Yoshida, T., et al., Phytochemistry, 24:1041-1046, 1985.
Yu et al., Chung. Kuo. Yao. Li. Hsueh. Pao. (Abstract), 15(2):103-106, 1994 .
Sim Keng-Yeow
Wan Min
Xu Hong-Xi
Zeng Fa-Quan
Dalhousie University
Gravelle Micheline
National University of Singapore
Spivack Phyllis G.
LandOfFree
Retrovirus protease inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Retrovirus protease inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Retrovirus protease inhibitors will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1375711