Retrovirus protease inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

562508, 562510, A61K 3119, C07C 6232, C07C 6238

Patent

active

059169192

ABSTRACT:
A compound composition and method of treating a retrovirus infection are disclosed. In particular, isolated triterpenes have been shown to have significant inhibitory activity against HIV-1.

REFERENCES:
patent: 4933169 (1990-06-01), Shanbrom
patent: 5086076 (1992-02-01), Herman
patent: 5204324 (1993-04-01), Shanbrom
patent: 5411733 (1995-05-01), Hozumi et al.
patent: 5527890 (1996-06-01), Rao et al.
Serra et al. Pharmacol. Res., 29(4), 359-66 (abstract), 1994.
Konoshima et al., J. Nat. Products, 50(6), 1167-70 (abstract), 1987.
Quere et al., Biochem. Biophys. Res. Commun., 227(2), 484-488, 1996.
Ryu et al., Arch. Pharmacol. Res., 16(4), 339-42 (abstract), 1993.
Brinkworth et al., Biochem. Biophys. Res. Commun., 188: 631-637, 1992.
De-Tommasi, J. Nat. Prod., (Abstract), 55(8):1067-1073, 1992.
Fujioka, T., et al., J. Nat. Prod., 57:243-247, 1994.
Hasegawa et al., Planta. Med., (Abstract), 60(3):240-243, 1994.
Hu, C. Q. et al., J. Nat. Prod., 57:42-51, 1994.
Ito, M. et al., N., Antiviral Res., 7: 127-137, 1987.
Kashiwada et al., J. Med. Chem., 39(5):1016-1017, 1996.
Konoshima et al., J. Nat. Prod., (Abstract) 58(9):1372-1377, 1995.
Li et al., J. Nat. Prod. (Abstract), 56(7):1130-1133, 1993.
McQuade, T.J., et al., Science, 247:454-456, 1990.
Mirmala, M., NUS term finds possible link to AIDS cure, "New Straits Time", Jun. 25, 1996.
Pengsuparp et al., J. Nat. Prod. (Abstract), 58(7):1024-1031, 1995.
Piacente, S. et al., J. Nat. Prod., 59:565-569, 1996.
Seelmeier, S. et al., Proc. Natl. Acad. Sci. USA, 85:6612-6616, 1988.
Shigenaga, S., et al., Phytochemistry, 24:115-118, 1985.
Soler et al., J. Med. Chem, 39(5):1069-1083, 1996.
Wang, S.N. et al., J. Med. Chem. 39: 2047-, 1996.
Xu, H. X., et al., Heterocycles, 38: 167-175, 1994.
Xu, H.X. et al., Phyto. Res., 10:207-210, 1996.
Xu, H.X. et al., J. Nat. Prod. 59(7):643-645, 1996.
Yoshida, T., et al., Chem. Pharm. Bull., 30:4245-4248, 1982.
Yoshida, T., et al., Phytochemistry, 24:1041-1046, 1985.
Yu et al., Chung. Kuo. Yao. Li. Hsueh. Pao. (Abstract), 15(2):103-106, 1994 .

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Retrovirus protease inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Retrovirus protease inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Retrovirus protease inhibitors will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1375711

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.