Retrovirus isolated from mantle histiocytes in mantle cell...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S006120, C435S325000, C435S810000, C530S388300, C530S389100, C536S023100, C536S023720

Reexamination Certificate

active

06924095

ABSTRACT:
The present invention features an isolated, intact virus associated with human lymphoma, and originally isolated from a mantle cell lymphoma, referred to herein as a mantle histiocyte retrovirus (MHRV). The invention also features compositions and methods for detecting MHRV, as well as methods and compositions for propagating MHRV in vitro, screening for anti-MHRV agents, and generation of attenuated MHRV strains.

REFERENCES:
patent: 5108920 (1992-04-01), Ng et al.
patent: 6149918 (2000-11-01), McGrath et al.
patent: 6242201 (2001-06-01), Lane et al.
Boller, et al.,“Characterization of the Antibody Response Specific for the Human Endogenous Retrovirus HTDV/HERV-K”, J. of Virology (Jun. 1997) vol. 71(6) pp. 4581-4588.
Boller, et al.,“Evidence that HERV-K is the Endogenous Retrovirus Sequence that Codes for the Human Tetatocarcinoma-Derived Retrovirus HTDV”, Virology 196, 349-353 (1993).
Clerici, et al.,“Immune Response to Antigens of Human Endogenous Retroviruses in Patients with Acute ir Stable Multiple Sclerosis”, Journal of Neuroimmunology, 99, pp. 173-182 (1999).
Lower, et al.,“The Viruses in all of us: Characteristics and Biological Significance of Human Endogenous Retrovirus Sequences”, Proc. Natl. Acad. Sci. vol. 93 pp. 5177-5184 (May 1996).
Nelson, et al.,“Molecular Investigations Implicate Human Endogenous Retroviruses as Mediators of Anti-Retroviral Antibodies in Autoimmune Rheumatic Disease”, Immunological Investigations 28(4), 277-289 (1999).
Eugene D. Sverdlov,“Retroviruses and Primate Evolution”, Bioassays 22: 161-171 (2000).
Tonjes, et al.,“Genome-Wide Screening, Cloning, Chromosomal Assignment and Expression of Full-Length Human Endogenous Type K”, Journal of Virology, vol. 73(11) pp. 9187-9195 (Nov. 1999).
Trabattoni, et al.,“Augmented Type 1 Cytokines and Human Endogenous Retroviruses Specific Immune Responses in Patients with Acute Multiple Sclerosis”, Journal of Neurovirology (2000) 6, Suppl 2, S38-S41.
Willer, et al.,“Two Groups of Endogenous MMTV Related Retroviral env Transcripts Expressed in Human Tissues”, Virus Genes 15:2, 123-133 (1997).
Yolken, et al.,“Endogenous Retroviruses and Schizophrenia”, Brain Research Reviews 31 (2000) 193-199.
McGrath, et al.,“Clonal HIV in the Pathogenesis of AIDS-Related Lymphoma”Infectious Causes of Cancer: Targets for Intervention Chapter 13 pp. 231-242.
Michael Tristem, “Identification and Characterization of Novel Human Endogenous Retrovirus Families by Phylogenetic Screening of the Human Genome Mapping Project Database” Journal of Virology pp. 3715-3730 (Apr. 2000).
Accession No. AF164609Homo sapiensendogenous retrovirus HERV-K101, complete sequence. Barbulescu et al., Molecular Genetics, (Jul. 2, 1999).
Accession No. AF164609, (Version AF164609.1)Homo sapiensendogenous retrovirus HERV-K101, complete sequence. Barbulescu et al., Molecular Genetics, (Jul. 2, 1999).
Accession No. M14123 Human endogenous . . . (Version M14123.1) Ono et al., Journal of Virology 60 (2), 589-598 (1986).
Accession No. AF164611 (Version AF164611.1)Homo sapiensendogenous retrovirus HERV-K103, complete sequence. Barbulescu et al., Molecular Genetics, (Jul. 2, 1999).
Accession No. AF164613Homo sapiensendogenous retrovirus HERV-K107, long terminal repeat, complete sequence. Barbulescu et al., Molecular Genetics, (Jul. 2, 1999).
Accession No. AF164614 (Version AF164614.1)Homo sapiensendogenous retrovirus HERV-K108, complete sequence. Barbulescu et al., Molecular Genetics, (Jul. 2, 1999).
Accession No. AF164615 (Version AF164615.1)Homo sapiensendogenous retrovirus HERV-K109, complete sequence. Barbulescu et al., Molecular Genetics, (Jul. 2, 1999).
Accession No. P10265 Endogenous retrovirus HERV-K10, putative protease (Version M14123.1) Ono et al., Journal of Virology 60 (2), 589-598 (1986).
Accession No. Y10392 Human endogenous retrovirus HERV-K, gag, protease and Pol gene, Partial (Version Y10392.1) Tonjes et al., Virology 223 (2), 280-291 (1997).
Neto et al., “Shotgun Sequencing of the Human Transcriptome with ORF Expressed Sequence Tags,” PNAS, vol. 97, No. 7, 3491-3496, Mar. 28, 2000.
Sugimoto et al., Transcriptionally Active HERV-K Genes: Identification, Isolation, and Chromosomal Mapping, Genomics 72, 137-144 (2001).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Retrovirus isolated from mantle histiocytes in mantle cell... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Retrovirus isolated from mantle histiocytes in mantle cell..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Retrovirus isolated from mantle histiocytes in mantle cell... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3482316

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.