Retrovirus capable of causing AIDS, antigens obtained from this

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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530389, 530403, 530826, 435 5, C07K 1500

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active

050307185

ABSTRACT:
The invention relates to a new variety of retroviruses designated Human Immunodeficiency virus Type II, HIV-II, samples of which have been deposited at CNCM as I-502 and I-532. It also concerns purified forms of the antigens which can be obtained from this virus, in particular from the gp 36 and gp 130-140 proteins. These various antigens are useful in medical diagnosis and kits, in particular by being placed in contact with serum of the patient to be diagnosed. Lastly, the invention relates to immunizing compositions, in particular containing at least one of glycoproteins gp 36 and gp 130-140.

REFERENCES:
patent: 4629783 (1986-12-01), Cosand
Sarngadharan et al., "Immunological Properties of HTLV-III Antigens Recognized by Sera in Patients with AIDS and AIDS-Related Complex and of Asymptomatic Carriers of HTLV-III Infection", Cancer. Res. 45 (1985) 4574s-4577s.

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