Retroviral vectors produced by producer cell lines resistant to

Details Retroviral vectors produced by producer cell lines resistant to Retroviral vectors produced by producer cell lines resistant to

1995-08-17

1999-09-14

Guzo, David

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Rodent cell, per se

435325, 435366, 435369, 435371, 4353201, C12N 510, C12N 1586

Patent

active

059522259

ABSTRACT:
Retroviral which are resistant to inactivation by human serum. The retroviral vectors are produced in a cell line which is resistant to lysis by human serum, such cell lines including the HOS, Mv-1-Lu, HT1080, TE671, and human 293 cell lines, as well as cell lines derived therefrom. Such retroviral vectors are especially useful as in vivo gene delivery vehicles.

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