Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1997-06-16
2000-10-17
Guzo, David
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 9113, 4353201, 435325, 435366, 536 231, 536 245, C12Q 168, C07H 2104, C12N 1585, A61K 4800
Patent
active
061329622
ABSTRACT:
This invention provides an infectious retrovirus having inserted between the 5' and 3' long terminal repeat sequences of the retrovirus a nucleic acid encoding an anti-HIV-type specific agent or a foreign nucleic acid under the control of a pol III promoter. Host cells containing the retroviral vectors of this invention also are provided. Further provided are methods of interfering with or preventing HIV viral replication in a cell infected with HIV or likely to be infected with HIV.
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Ho Anthony
Leavitt Markley C.
Ojwang Joshua O.
Wong-Staal Flossie
Yamada Osamu
Guzo David
The Regents of the University of California
Wang Andrew
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