Retrotransposon and methods

Details Retrotransposon and methods Retrotransposon and methods

1996-12-20

1999-11-02

Degen, Nancy

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

43525411, 435325, 435462, 536 231, 536 232, C12Q 168, C12N 1587, C12N 116, C07H 2104

Patent

active

059767952

ABSTRACT:
The present disclosure provides retrotransposons and retrotransposon derivatives and methods for their uses. Specifically, the present invention provides Ty5-6p and derivatives. Ty5-6p and its derivatives integrate preferentially in the genome of eukaryotes in silent chromatin and in regions like silent chromatin. Ty5-6p insertions can be used to regulate the life span of cells, to genetically mark cells, to deliver gene therapy and to identify genes involved in development and in senescence.

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