Retrograde perfusion

Details Retrograde perfusion Retrograde perfusion

1987-08-07

1989-09-19

Rosenbaum, C. Fred

Surgery

Means for introducing or removing material from body for...

Material introduced into and removed from body through...

128655, 128658, 604 35, 604 43, 604101, 604121, A61B 106

Patent

active

048677426

ABSTRACT:
Tumors in the body of a patient are studied in situ by a monitor, such as computer assisted tomography, X-ray or the like, while optimal flow paths through the tumor area are established. A catheter with a suction lumen and an infusion lumen, with seals associated with each, is placed in the patient's vein near the tumor. Flow is then sealed in the vein with the infusion seal. A carrier medium dye is injected into the tumor at selected flow rates and differential pressures. Flow of the dye through the tumor is observed on the monitor to determine optimal retrograde perfusion paths through the tumor for the selected flow rates and differential pressures. Once the optimal perfusion paths are noted, microspheres with active ingredients, such as chemotherapy, can be selectively perfused through each of the paths in the tumor at desired flow rates, pressures and active ingredient dosages. Alternatively, microspheres with different active ingredients can be selectively introduced through the tumor in different paths at desired active ingredient dosages and established flow rates and pressures.

REFERENCES:
patent: 2854982 (1958-10-01), Pagano
patent: 3888239 (1975-06-01), Rubenstein
patent: 4192302 (1980-03-01), Boddie
patent: 4445892 (1984-05-01), Hussein et al.
patent: 4708718 (1987-11-01), Daniels
patent: 4709703 (1987-12-01), Lazarow et al.
patent: 4714460 (1987-12-01), Calderon
Folkman, J., "The Vascularization of Tumors", pp. 59-73.
Kato, T., "Arterial Chemoembolization with Microencapsulated Anticancer Drug", JAMA, Mar. 20, 1981, vol. 245, No. 11, pp. 1123-1127.

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