Retro-inverso peptides derived from leukemia inhibitory factor

Details Retro-inverso peptides derived from leukemia inhibitory factor Retro-inverso peptides derived from leukemia inhibitory factor

2006-09-19

2006-09-19

Campell, Bruce R. (Department: 1654)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S002600, C514S012200, C530S300000, C530S324000, C530S325000, C530S326000

Reexamination Certificate

active

07109168

ABSTRACT:
Retro-inverso peptides derived from leukemia inhibitory factor (LIF) having between 18 and about 40 amino acids and including the sequence shown in SEQ ID NO: 1. These peptides have the same activity as native LIF and also have neurotrophic activity. Because of the D-amino acid linkage in the peptides, they are less susceptible to proteolytic degradation in vivo.

REFERENCES:
patent: 4698327 (1987-10-01), Nagarajan et al.
patent: 5376544 (1994-12-01), Lazarus et al.
patent: 5700909 (1997-12-01), O'Brien
patent: 5843892 (1998-12-01), Patterson
patent: 6217871 (2001-04-01), Rose et al.
patent: 6586403 (2003-07-01), Mathison et al.
patent: WO 9839357 (1998-09-01), None
Y. Takahama, et al. Oncogene (1998) 16, pp. 3189-3196.
J. Rudinger. In: Peptide Hormones, JA Parsons, Ed. (1976) 1-7.
D. Voet and J.G. Voet. Biochemistry, 2nd Edition.(1995), pp. 235-241.
D.E. Smilek, et al. Proc. Natl. Acad. Sci. USA (1991) 88, pp. 9633-9637.
W.S. Messer, “Vasopressin and Oxytocin”, web document updated Apr. 3, 2000; <http://www.neurosci.pharm.utoledo.edu/MBC3320/vasopressin.htm>; 5 pages.
S. Rudikoff, et al. Proc. Natl. Acad. Sci. USA (1982) 79, pp. 1979-1983.

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