Retro-inverso C-terminal hexapeptide analogues of substance P

Details Retro-inverso C-terminal hexapeptide analogues of substance P Retro-inverso C-terminal hexapeptide analogues of substance P

1985-01-09

1987-01-20

Phillips, Delbert R.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Containing at least one abnormal peptide link, e.g., gamma...

530329, C07K 702

Patent

active

046380469

ABSTRACT:
New retro-inverso peptides and peptide derivatives in the form of analogues of C-terminal hexapeptide fragments of Substance P, which are pharmacologically active, possess prolonged action with time, and are of general formula (I): ##STR1## they being useful as vasedilators.

REFERENCES:
patent: 3862114 (1975-01-01), Scandrett
patent: 4439360 (1984-03-01), Verdini et al.
patent: 4472305 (1984-09-01), Hansen et al.
patent: 4481139 (1984-11-01), Folkers et al.
patent: 4485099 (1984-11-01), Boger et al.

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