Retrievable bioartificial implants having dimensions allowing ra

Details Retrievable bioartificial implants having dimensions allowing ra Retrievable bioartificial implants having dimensions allowing ra

1998-08-03

2000-12-26

Milano, Michael J.

Prosthesis (i.e., artificial body members), parts thereof, or ai

Implantable prosthesis

Tissue

A61F 202

Patent

active

061652253

ABSTRACT:
Bioartificial implants and methods for their manufacture and use are described, particularly bioartificial pancreases. In particular, the implants may be thin sheets which enclose cells, may be completely biocompatible over extended periods of time and may not induce fibrosis. The high-density-cell-containing thin sheets are preferably completely retrievable, and have dimensions allowing maintenance of optimal tissue viability through rapid diffusion of nutrients and oxygen and also allowing rapid changes in the secretion rate of insulin and/or other bioactive agents in response to changing physiology. Implantations of living cells, tissue, drugs, medicines and/or enzymes, contained in the bioartificial implants may be made to treat and/or prevent disease.

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