Retinoid-like compounds

Details Retinoid-like compounds Retinoid-like compounds

1995-06-02

1996-06-04

Dees, Jose G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560 48, 560100, 560 57, 562455, 562461, 562467, 562471, 562490, 564169, 564174, 564176, 564180, 568705, 568808, C07C26100, C07C 6976, C07C22900

Patent

active

055234577

ABSTRACT:
This invention relates to a retinoid mpound of formula I ##STR1## in which Y is --CO--NH--, --CR.sup.2 .dbd.CR.sup.3 --, --CO--O--, --O--CO--, --C(.dbd.S)--NH--, --C.tbd.C--, --O--CH.sub.2 --, --CH.sub.2 --O--, or --CH.sub.2 --CH.sub.2 --;

REFERENCES:
patent: 4876381 (1989-10-01), Lang et al.
Hiroyuki Kagechika, et al, "Retinobenzoic Acids. 1. Structure-Activity Relationships of Aromatic Amides with Retinoidal Activity", Journal of Medicinal Chemistry, 31, No. 11, pp. 2182-2192, 1988. (Correction included, Journal of Medicinal Chemistry, 32, No. 12, p. 2583, 1989).
Peter Loeliger, et al, "Arotinoids, a New Class of Highly Active Retinoids", Eur. J. Med. Chem., Chimica Therapeutica, 15, No. 1, pp. 9-15, 1980.

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