Retinoid derivatives with antiangiogenic, antitumoral and...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ether doai

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C562S469000, C562S492000

Reexamination Certificate

active

07449495

ABSTRACT:
Described and claimed are compounds of Formula (I) in which R, R′, R″, A, and D have the meanings described in the text, as useful agents in the cure of pathologies characterized by altered angiogenesis and as antitumorals.

REFERENCES:
patent: 5547983 (1996-08-01), Charpentier
patent: 7053071 (2006-05-01), Dawson et al.
Zhang et al. Blood, 2002, 100(8), pp. 2917-2925.
Dawson, et al., An Adamantyl-Substituted Retinoid-Derived Molecule That Inhibits Cancer Cell Growth And Angiogenesis By Inducing Apoptosis And Binds To Small Heterodimer Partner Nuclear Receptor: Effects Of Modifying Its Carboxylate Group On Apoptosis, Proliferation, And Protein-Tyrosine Phosphatase Activity, Journal of Medicinal Chemistry (2007) pp. A-R.
Tittley et al., J. Med. Chem. (1989) vol. 32, pp. 1814-1820.
RN 146966-12-3 CAPLUS.
Database Crossfire Beilstein Online. Database Accession No. 3358409 - Beilstein Institute zur Forderung der chemischen Wissenschaften, frankfurt am Main, DE; Abstract & Mudrovcic: Monatsh. Chem., vol. 34, 1913, p. 1428.
Database Crossfire Beilstein Online. Database Accession No. 7997805 - Beilstein Institute zur Forderung der chemischen Wissenschaften, IFranfurt am Main, DE; Abstract & Krestinina, T.B.: Russ. J. Org. Chem., vol. 33, No. 7, 1997, pp. 1044-1045.
Database Crossfire Beilstein Online. Database Accession No. 2663218 - Beilstein Institute zur Forderung der chemischen Wissenschaften, Frankfurt am Main, DE; Abstract & Rabiloud, G. et al: Bull. Soc. Chem. Fr., 1977, pp. 281-287.
Jefferson, et al., Biphenylcarboxamide Derivatives as Antagonists of Platelet-Activating Factor, J. Med. Chem., vol. 32, No. 8, 1989, pp. 1814-1820.
Charpenter, et al., Synthesis, Structure-Affinity Relationships, And Biological !Activities Of Ligands Binding To Retinoic Acid Receptor Subtypes, Journal Of Medicinal Chemistry, vol. 38, No. 26, 1995, pp. 4993-5006.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Retinoid derivatives with antiangiogenic, antitumoral and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Retinoid derivatives with antiangiogenic, antitumoral and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Retinoid derivatives with antiangiogenic, antitumoral and... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4030119

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.