Retinoid carbohydrates

Details Retinoid carbohydrates Retinoid carbohydrates

1984-12-03

1986-01-21

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 187, 536 53, 536119, C07H 1302

Patent

active

045658633

ABSTRACT:
The novel retinoids of the formula ##STR1## wherein R represents a residue of a sugar attached ester-wise or a residue of an amino-sugar attached amide-wise or of derivatives of such sugars and n is 1 or 2,
can be used as medicaments, e.g. for the treatment of neoplasms, acne and psoriasis. These compounds are obtained by reacting a sugar or an aminosugar or a derivative thereof with a reactive derivative of 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid, optionally followed by the modification of reactive groups present in the reaction product.

REFERENCES:
patent: 3219657 (1965-11-01), Gaertner
patent: 4215215 (1980-07-01), Bollag
patent: 4316983 (1982-02-01), Bollag
patent: 4388312 (1983-06-01), Terao et al.

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