Retinoblastoma gene-cancer suppressor and regulator

Details Retinoblastoma gene-cancer suppressor and regulator Retinoblastoma gene-cancer suppressor and regulator

1995-06-07

1999-12-07

Campbell, Eggerton A.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C12Q 168

Patent

active

059981342

ABSTRACT:
This invention relates in general to a genetic control of retinoblastoma and regulation of carcinogenicity. In particular this invention relates to the cloning, isolation, identification and sequencing of the retinoblastoma gene. The invention also relates to the method of use of the cloned retinoblastoma gene cDNA as a tool for diagnosing retinoblastoma, osteosarcoma and fibrosarcoma. Finally, the invention relates to the control and regulatory mechanisms and functions of the retinoblastoma gene in the oncogenesis.

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