Retinal tissue implantation method

Surgery – Miscellaneous – Methods

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623 4, 606107, A61B 1900

Patent

active

059412500

ABSTRACT:
The disclosure relates to a method and instrument for implanting retinal tissue into the subretinal space of the eye comprising the steps of inducting a fragment of retinal tissue into a tubular nozzle of an instrument by retracting a mandrel telescoped internally of the nozzle, incising the pars plana region of the eye, incising the retina of the eye to expose a subretinal target area, inserting the nozzle of the instrument through the incisions in the pars plana and retina of the eye, orientating an open end of the nozzle over the target area of the retina, and retracting the nozzle relative to the mandrel of the instrument to deposit the tissue in the target area of the eye.

REFERENCES:
patent: 4955889 (1990-09-01), Van Gent
patent: 5108421 (1992-04-01), Fowler
patent: 5468246 (1995-11-01), Blake
patent: 5817075 (1998-10-01), Giungo
DiLoreto, Jr., "Cyclosporine Treatment Promotes Survival of Human Fetal Neural Retina Transplanted to the Subretinal Space of the Light-Damaged Fischer 344 Rat", Experimental Neurology, 140: 37-42, 1996.
DiLoreto, Jr., "Storage of Human Fetal Retina in Optisol prior to Subretinal Transplantation", Cell Transplantation, vol. 5, No. 5, pp. 553-561, 1996.
del Cerro, "Intraocular Retinal Transplants", The Journal of Cell Biology, Abstracts, vol. 97, No. 5, Part 2, Nov. 1983.
del Cerro, "The First Decade of Continuous Progress in Retinal Transplantation", Microscopy Research and Technique, 36:130-141, 1997.

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