Retinal, derivatives and their therapeutic use

Details Retinal, derivatives and their therapeutic use Retinal, derivatives and their therapeutic use

1989-04-07

1992-03-03

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514468, 514529, 514470, 514693, 514698, 514701, 514703, 514715, 514725, 514859, 514863, A61K 31075, A61K 3111, A61K 3133

Patent

active

050933604

ABSTRACT:
Therapeutic as well as preventive measures to improve cosmetic conditions and to alleviate the symptoms of dermatologic disorders with retinal and its derivatives is disclosed. Cosmetic conditions and dermatologic disorders in humans and domestic animals in which retinal and its derivatives may be useful include age spots, wrinkles, warts, eczema, seborrheic keratoses, acne, oily skin, psoriasis, dandruff, xerosis, inflammatory and pruritic skin, disturbed keratinization skin changes associated with aging and possibly viral infections. Retinal and its derivatives include their stereoisomers, for example, all-trans, 13-cis, 11-cis, 9-cis, 7-cis, 11,13-cis and 9,13-cis vitamin A aldehydes, their hydrate, hemiacetal and acetal forms, and their adduct compounds. Compositions containing retinal or its derivative may be administered systemically such as orally, or topically to the affected areas of the skin.

REFERENCES:
patent: 3932665 (1976-01-01), Van Scott et al.
patent: 4034114 (1977-07-01), Yu et al.
patent: 4888342 (1989-12-01), Kligman

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