Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Rodent cell – per se
Reexamination Certificate
2005-04-12
2005-04-12
Guzo, David (Department: 1636)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Rodent cell, per se
C435S325000
Reexamination Certificate
active
06878544
ABSTRACT:
The invention features retina-derived (retinal endothelial or retinal epithelial pigment) cell lines with extended life-span and capable of being implanted in the retina and of carrying a therapeutic substance to the eye and to the central nervous system. Such lines can also be used as a model for studying blood central nervous system interfaces. These lines are derived from primary retinal cultures selected from the group consisting of primary retinal endothelial cells and primary retinal epithelial cells, comprise a polynucleotide containing an oncogene, which polynucleotide is optionally associated with at least one selection gene, and have the morphological characteristics and at least the expression characteristics of the surface antigens of corresponding primary cultures.
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Adamson Peter
Greenwood John
Lund Raymond
Tao Weng
Elrifi, Esq. Ivor R.
Guzo David
Mintz Levin Cohn Ferris Glovsky and Popeo P.C.
Neurotech SA
Stock, Esq. Christina K.
LandOfFree
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