Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is inorganic
Reexamination Certificate
2006-09-26
2006-09-26
Le, Long V. (Department: 1641)
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
Carrier is inorganic
C435S174000, C435S175000, C435S176000, C435S177000, C435S178000, C435S179000, C435S180000, C435S181000, C435S182000, C435S187000, C435S188000, C435S287100, C435S287200, C435S287700, C435S287900, C435S288300, C435S288400, C435S288600, C435S803000, C435S814000, C435S815000, C435S970000, C435S973000, C435S091500, C436S518000, C436S523000, C436S524000, C436S526000, C436S527000, C436S528000, C436S529000, C436S530000, C436S531000, C436S532000, C436S535000, C436S161000, C436S162000, C436S173000, C436S174000, C436S
Reexamination Certificate
active
07112453
ABSTRACT:
This invention provides methods of retentate chromatography for resolving analytes in a sample. The methods involve adsorbing the analytes to a substrate under a plurality of different selectivity conditions, and detecting the analytes retained on the substrate by desorption spectrometry. The methods are useful in biology and medicine, including clinical diagnostics and drug discovery.
REFERENCES:
patent: 3151982 (1964-10-01), Corrsin
patent: 3288604 (1966-11-01), Corrsin
patent: 3669841 (1972-06-01), Miller
patent: 3896661 (1975-07-01), Parkhurst et al.
patent: 4126554 (1978-11-01), Rainin
patent: 4259572 (1981-03-01), Brunnee et al.
patent: 4313908 (1982-02-01), Gupta
patent: 4468468 (1984-08-01), Benninghoven et al.
patent: 4527059 (1985-07-01), Benninghoven et al.
patent: 4587020 (1986-05-01), Nakagawa et al.
patent: 4752562 (1988-06-01), Sheiman et al.
patent: 4820648 (1989-04-01), Caprioli et al.
patent: 4833093 (1989-05-01), Malmqvist et al.
patent: 4963263 (1990-10-01), Kauvar
patent: 4988879 (1991-01-01), Zare et al.
patent: 5010175 (1991-04-01), Rutter et al.
patent: 5037611 (1991-08-01), Ledford, Jr.
patent: 5045694 (1991-09-01), Beavis et al.
patent: 5083020 (1992-01-01), Takahashi
patent: 5118937 (1992-06-01), Hillenkamp et al.
patent: 5133866 (1992-07-01), Kauvar
patent: 5135627 (1992-08-01), Soane
patent: 5223409 (1993-06-01), Ladner et al.
patent: 5260571 (1993-11-01), Cottrell et al.
patent: 5288644 (1994-02-01), Beavis et al.
patent: 5338659 (1994-08-01), Kauvar
patent: 5340474 (1994-08-01), Kauvar
patent: 5356784 (1994-10-01), Kauvar
patent: 5376249 (1994-12-01), Afeyan et al.
patent: 5382793 (1995-01-01), Weinberger et al.
patent: 5445934 (1995-08-01), Fodor et al.
patent: 5453199 (1995-09-01), Afeyan et al.
patent: 5453247 (1995-09-01), Beavis et al.
patent: 5498545 (1996-03-01), Vestal
patent: 5538897 (1996-07-01), Yates, III et al.
patent: 5541070 (1996-07-01), Kauvar
patent: 5547835 (1996-08-01), Koster
patent: 5571698 (1996-11-01), Ladner et al.
patent: 5587293 (1996-12-01), Kauvar et al.
patent: 5599901 (1997-02-01), Kauvar
patent: 5605798 (1997-02-01), Koster
patent: 5622824 (1997-04-01), Koster
patent: 5624711 (1997-04-01), Sundberg et al.
patent: 5705813 (1998-01-01), Apffel et al.
patent: 5716825 (1998-02-01), Hancock et al.
patent: 5719060 (1998-02-01), Hutchens et al.
patent: 5741462 (1998-04-01), Nova et al.
patent: 5770272 (1998-06-01), Biemann et al.
patent: 5780232 (1998-07-01), Arlinghaus et al.
patent: 5808300 (1998-09-01), Caprioli
patent: 5821060 (1998-10-01), Arlinghaus et al.
patent: 5834195 (1998-11-01), Benkovic et al.
patent: 5846708 (1998-12-01), Hollis et al.
patent: 5854486 (1998-12-01), Dreyfus
patent: 5882496 (1999-03-01), Northrup et al.
patent: 5955729 (1999-09-01), Nelson et al.
patent: 5985153 (1999-11-01), Dolan et al.
patent: 6004770 (1999-12-01), Nelson
patent: 6013188 (2000-01-01), Terstappen et al.
patent: 6030917 (2000-02-01), Weinberg et al.
patent: 6071610 (2000-06-01), Jarrell et al.
patent: 6093541 (2000-07-01), Nelson
patent: 6127005 (2000-10-01), Lehman et al.
patent: 6136182 (2000-10-01), Dolan et al.
patent: 6207369 (2001-03-01), Wohlstadter et al.
patent: 6225047 (2001-05-01), Hutchens et al.
patent: 6288390 (2001-09-01), Siuzdak et al.
patent: 6316266 (2001-11-01), Nelson
patent: 6414306 (2002-07-01), Mayer-Posner et al.
patent: 6419881 (2002-07-01), Weinberg et al.
patent: 6440745 (2002-08-01), Weinberg et al.
patent: 6498039 (2002-12-01), Nelson
patent: 6660159 (2003-12-01), Terstappen et al.
patent: 6790366 (2004-09-01), Terstappen et al.
patent: 2281122 (1995-02-01), None
patent: WO 89/03430 (1989-04-01), None
patent: WO 89/09088 (1989-10-01), None
patent: WO 89/10977 (1989-11-01), None
patent: WO 91/02961 (1991-03-01), None
patent: WO 91/18980 (1991-12-01), None
patent: WO 91/19818 (1991-12-01), None
patent: WO 92/18619 (1992-10-01), None
patent: WO 93/24834 (1993-12-01), None
patent: WO 94/06920 (1994-03-01), None
patent: WO 94/28418 (1994-12-01), None
patent: WO 95/00530 (1995-01-01), None
patent: WO 95/35505 (1995-12-01), None
patent: WO 97/10365 (1996-03-01), None
patent: WO 96/36986 (1996-11-01), None
patent: WO 96/37777 (1996-11-01), None
patent: WO 96/40888 (1996-12-01), None
patent: WO 97/09068 (1997-03-01), None
Hutchens TW & Yip TT. New desorption strategies for the mass spectrometric analysis of macromolecules. Rapid Commun. Mass Spectrom. 1993; 7:576-580.
Chevrier et al., “Matrix-assisted UV Laser Desorption of Proteins Using a 600 Picosecond Nitrogen Laser,”39th ASMS Conf. on Mass Spectrometry and Allied Topics, pp. 933-934.
Dougruel et al., “Rapid Tryptic Mapping Using Enzymatically Active Mass Spectrometer Probe Tips,”Anal. Chem, 67;4343-4348 (1995).
Hefta et al., “Analysis of Highly Glycosylated or Hydrophobic Membrane Proteins by Laser Desorption Time-Of-Flight Mass Spectrometry,”39th ASMA Conf. on Mass Spectrometry and Allied Topics, pp. 1416-1417.
Jonsson et al., “Plasma Desorption Mass Spectrometry of Peptides and Proteins Adsorbed on Nitrocellulose,”Anal. Chem., 58:1084-1087 (1986).
Karas et al., “Principles and applications of matrix-assisted UV-laser desorption/ionization mass spectrometry,”Analytica Chimica Acta, 241:175-185 (1990).
Klarskov et al., “Plasma Desorption Mass Spectrometry of Proteins Transferred from Gels After Sodium Dodecyl Sulphate-Polyacrylamide Gel Electrophoresis,”Biol. Mass Spectrometry, 22:433-440 (1993).
Krone et al., “BIA/MS: Interfacing Biomolecular Interaction Analysis with Mass Spectrometry,”Anal. Biochem., 244:124-132 (1997).
Krone et al., “Mass Spectrometric Immunoassay, in: Ultrasensitive Biochemical Diagnostics,” Cohn et al. (Eds.),Proc. SPIE, 2680:415-421 (1996).
Macfarlane et al., “Mass Spectrometric Study of Ion Adsorption on Poly(ethylene terephthalate) and Polypropylene Surfaces,”Anal. Chem., 58:1091-1097 (1986).
Mock et al., “Sample Immoblization Protocols for Matrix-assisted Laser-desorption Mass Spectrometry,”Rapid Communications in Mass Spectrometry, 6:233-238 (1992).
Nelson et al., “Mass Spectrometric Immunoassay,”Anal. Chem., 67(7):1153-1158 (1995).
Nelson et al., “Peptide Characterization Using Bioreactive Mass Spectrometer Probe Tips,”Rapid Commun. Mass Spectrom., 9:1380-1385 (1995).
Papac et al., “Direct Analysis of Affinity-Bound Analytes by MALDI/TOF MS,”Anal. Chem., 66:2609-2613.
Van De Water et al., “Detection of Molecular Determinants in Complex Biological Systems Using MALDI-TOF Affinity Mass Spectrometry,”Mass Spectrometry of Proteins and Peptides, Humana Press, pp. 453-459.
Vestling et al., “Polyvinylidene difluoride (PVDF): an interface for gel electrophoresis and matrix-assisted laser desorption/Ionization mass spectrometry,”Biochemical Applications of Mass Spectrometry, 22:547-551 (1994).
Woods et al., “Enzymatic digestion on the sample foil as a method for sequence determination by plasma desorption mass spectrometry: the primary structure of porpoise relaxin,”Int. J. Mass Spectrometry and Ion Processes, 111:77-88 (1991).
Zaluzec et al., “Direct Matrix-Assisted Laser Desorption Ionization Mass Spectrometric Analysis of Proteins Immobilized on Nylon-Based Membranes,”J. Am.Soc. Mass Spectrom., 5:230-237 (1994).
Zaluzec et al., “MALDI-Mass Spectrometric Analysis of Proteins Immobilized on Nylon-based Membranes,”41st ASMS Conf. on Mass Spectrometry, pp. 436a-436b (1993).
Hutchens T. William
Yip Tai-Tung
Ciphergen Biosystems Inc.
Le Long V.
Townsend & Townsend & Crew LLP
Venci David J.
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