Restriction endonucleas DRA III

Details Restriction endonucleas DRA III Restriction endonucleas DRA III

1988-05-03

1989-09-05

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435199, C12P 1934, C12N 922

Patent

active

048638587

ABSTRACT:
The present invention teaches a restriction endonuclease which recognizes and cleaves the following palendromic sequence of nucleic acids at that point indicated by the arrows: ##STR1## One source of the endonuclease is Deinococcus radiophilus (OSM 20551). The endonuclease is useful in analyzing DNA sequences and for preparing DNA fragments for purposes such as making DNA probes.

REFERENCES:
deWit, C. M., Dekker, B. M. M., Neele, A. C. and del Vaarb, A. (1985), FEBS Letters, 180(2), 219-223.
Grosskopf, R., Wolf, W. and Kessler, C. (1985), Nucleic Acids Research 13(5), 1517.1528.
Roberts, R. J. (1985), Nucleic Acids Research 13 (suppl), p. 165.
Roberts, R. J. (1984) Nucleic Acids Research 12 (suppl.), p. 167.
Purvis, I. J. and Moseley, B. E. B. (1983) Nucleic Acids Research 11(16), 5467-5474.
Lambda II (Hendrix, R. W., et al., Eds.) (1983), Appendix II, Cold Spring Harbor Laboratory.

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