Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing
Patent
1992-11-06
1995-05-09
Parr, Margaret
Organic compounds -- part of the class 532-570 series
Organic compounds
Oxygen containing
568332, 435177, 435180, C07C 4900, C12N 1100
Patent
active
054140757
ABSTRACT:
A multifunctional reagent is provided that is useful for the attachment of desired molecules to support surfaces. A reactive reagent molecule of the invention is "restrained" in that it is conformationally and/or chemically restricted from reacting with either itself or with other molecules of the same reagent. Upon activation, this feature causes the attachment of less than all of the reactive sites of the multifunctional reagent to a surface, thereby leaving the remaining sites free to react with molecules desired to be immobilized onto the surface.
REFERENCES:
patent: 4722906 (1988-02-01), Guire
patent: 4973493 (1990-11-01), Guire
patent: 4979959 (1990-12-01), Guire
patent: 5002582 (1991-03-01), Guire et al.
Cazaux et al., Tetrahedron Letters 30:1369-1372 (1989) "A Barium Selective Macrocyclic Tetralactam . . . ".
Yamamoto et al., Tetrahedron Letters 27:49-50 (1986) "Restricted Internal Rotation . . . "
Kroschwitz, "Plastics", pp. 462-464, in Concise Encyclopedia of Polymer Science and Engineering, ed., John Wiley and Sons, 1990.
Jentoft, N. and D. G. Dearborn, J. of Biol. Chem. 254:4359 (1979).
Jemmerson, R., "Antigenicity and Native Structure of Globular Proteins: Low Frequency of Peptide Reactive Antibodies", Proc. Nat. Acad. Sci. USA, 84:9180, 1987.
Stevens, F. J., "Considerations of the Interpretation of the Specificity of Monoclonal Antibodies Determined in Solid-Phase Immunoassays," in Immunochemistry of Solid-Phase Immunoassay, J. E. Butler, ed., CRC Press, 233, 1991.
Jemmerson, R., "Multiple Overlappings Epitopes in the Three Antigenic Regions of Horse Cytochrome c," J. Immunol. 128:213, 1987.
Hastings Charles A.
Swan Dale G.
BSI Corporation
Campbell Eggerton
Parr Margaret
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