Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1998-06-09
2000-10-31
Carlson, Karen Cochrane
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
424 91, 530350, 530352, 435 4, G01N 3353, C12Q 100, C07K 100, A61K 3816
Patent
active
061400610
ABSTRACT:
The invention provides response regulator polypeptides and polynucleotides encoding response regulator polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing response regulator polypeptides to screen for antibacterial compounds.
REFERENCES:
Volz, Karl. Structural Conservation in the CheY Superfamily. 32(44): 11741-11753, Nov. 9, 1993.
Swanson, et al., "Histidine and Aspartate Phosphorylation: Two-Component Systems and the Limits of Homology", Trends in Biochemical Sciences, vol. 19, No. 11, pp. 485-490, Nov. 1, 1994.
Seki, et al., "Nucleotide Sequence of the Bacillus subtilis phoR Gene", Journal of Bacteriology, vol. 170, No. 12, pp. 5935-5938, Dec. 1, 1988.
European Search Report completed Oct. 27, 1999 from corresponding European Application No. 98304775.4, filed Jun. 17, 1998.
Seki, et al., "Cloning and Nucleotide Sequence of phoP, the Regulatory Gene for Alkaline Phosphatase and Phosphodiesterase in Bacillus subtilis", Journal of Bacteriology, vol. 169, No.7, pp. 2913-2916, Jul., 1987.
Biswas Sanjoy
Throup John
Wallis Nicola Gail
Zalacain Magdalena
Carlson Karen Cochrane
Deibert Thomas S.
Gimmi Edward R.
King William T.
Schnizer Holly
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