Response regulator

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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Details

424 91, 530350, 530352, 435 4, G01N 3353, C12Q 100, C07K 100, A61K 3816

Patent

active

061400610

ABSTRACT:
The invention provides response regulator polypeptides and polynucleotides encoding response regulator polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing response regulator polypeptides to screen for antibacterial compounds.

REFERENCES:
Volz, Karl. Structural Conservation in the CheY Superfamily. 32(44): 11741-11753, Nov. 9, 1993.
Swanson, et al., "Histidine and Aspartate Phosphorylation: Two-Component Systems and the Limits of Homology", Trends in Biochemical Sciences, vol. 19, No. 11, pp. 485-490, Nov. 1, 1994.
Seki, et al., "Nucleotide Sequence of the Bacillus subtilis phoR Gene", Journal of Bacteriology, vol. 170, No. 12, pp. 5935-5938, Dec. 1, 1988.
European Search Report completed Oct. 27, 1999 from corresponding European Application No. 98304775.4, filed Jun. 17, 1998.
Seki, et al., "Cloning and Nucleotide Sequence of phoP, the Regulatory Gene for Alkaline Phosphatase and Phosphodiesterase in Bacillus subtilis", Journal of Bacteriology, vol. 169, No.7, pp. 2913-2916, Jul., 1987.

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